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- W2017514897 abstract "Purpose.: To determine the level of hepatocyte growth factor (HGF) in the aqueous humor of patients with retinitis pigmentosa (RP). Methods.: This was a prospective, comparative control study. Aqueous humor samples were collected from the eyes of 15 RP patients. The level of HGF was determined with a commercially available enzyme-linked immunoabsorbent assay kit. The control group was composed of aqueous samples from 15 patients about to undergo cataract surgery with no other ocular or systemic diseases. Results.: The concentration of HGF was markedly higher in the aqueous humor of the patients with RP than in that of the control subjects (Mann–Whitney U test, P < 0.001). The level of HGF was 958.75 ± 271.52 (mean ± SD) pg/mL in the eyes of the RP patients and 403.52 ± 116.27 pg/mL in eyes of the control group. Conclusions.: The concentration of HGF in aqueous humor is higher among patients with RP than in non-RP subjects. This finding provides new evidence that should be taken in account when considering HGF as a neuroprotective treatment for patients with RP." @default.
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- W2017514897 date "2010-06-01" @default.
- W2017514897 modified "2023-10-18" @default.
- W2017514897 title "Aqueous Humor Levels of Hepatocyte Growth Factor in Retinitis Pigmentosa" @default.
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- W2017514897 doi "https://doi.org/10.1167/iovs.09-4390" @default.
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