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• W2017538797 endingPage "257" @default.
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• W2017538797 abstract "The Pd- or Ni-catalyzed cross-coupling reactions of organometals containing Zn, Al, Zr, and B as well as related reactions of Mg and several other metals collectively represent the most widely applicable organic skeleton construction method discovered and developed over the past several decades, allowing the synthetic chemists to synthesize practically all types of organic compounds. Some of the seminal and critically important discoveries and early developments in the 1970s as well as their current scope (Tables 2 and 3) are briefly discussed. Some of the notable discoveries and developments include (1) identification of superior properties of Pd relative to Ni, (2) the broad scope of Pd- or Ni-catalyzed cross-coupling with respect to metal counter cations including Zn, Al, Zr, B, and Mg, (3) the hydrometallation–Pd-catalyzed cross-coupling tandem processes for selective syntheses of alkenes, dienes, oligoenes, and oligoenynes, (4) double metal catalysis involving Pd or Ni and added metal compounds containing Zn, In, Li, and others, and (5) realization of high turnover numbers (≥103–105) through the use of chelating phosphines, such as DPEphos and dppf. In these reactions, the metal counter cations in organometals and Pd or Ni are to work successively via transmetallation. The Zr-catalyzed alkyne carboalumination and the Zr-catalyzed asymmetric carboalumination of alkenes (ZACA reaction) have provided efficient and selective routes to methyl-branched (E)-trisubstituted alkenylalanes and 2-substituted chiral alkylalanes, respectively. These reactions provide two additional examples of prototypical transition metal-catalyzed organometallic reactions. Significantly, they can be readily combined with the Pd- or Ni-catalyzed cross-coupling for the synthesis of trisubstituted alkenes embracing a wide variety of natural products, such as terpenoids, carotenoids, and others, as well as various chiral organics including deoxypolypropionates and saturated terpenoids. The Zr-catalyzed alkyne carboalumination has been applied to the synthesis of well over 100 complex natural products (Table 4), while the ZACA reaction has been transformed from a mere scientific novelty to a full-fledged asymmetric synthetic method that is catalytic in both transition metal (Zr) and chiral auxiliaries through a series of breakthroughs (Schemes 12–17)." @default.
• W2017538797 created "2016-06-24" @default.
• W2017538797 creator A5049086283 @default.
• W2017538797 date "2007-01-15" @default.
• W2017538797 modified "2023-10-17" @default.
• W2017538797 title "Transition Metal-Catalyzed Organometallic Reactions that Have Revolutionized Organic Synthesis" @default.
• W2017538797 cites W1491128627 @default.
• W2017538797 cites W1541982473 @default.
• W2017538797 cites W1559544948 @default.
• W2017538797 cites W1863307104 @default.
• W2017538797 cites W1963772312 @default.
• W2017538797 cites W1965347482 @default.
• W2017538797 cites W1965536938 @default.
• W2017538797 cites W1965884680 @default.
• W2017538797 cites W1966115069 @default.
• W2017538797 cites W1967696920 @default.
• W2017538797 cites W1968290497 @default.
• W2017538797 cites W1968324728 @default.
• W2017538797 cites W1968481068 @default.
• W2017538797 cites W1969368344 @default.
• W2017538797 cites W1970234358 @default.
• W2017538797 cites W1971249363 @default.
• W2017538797 cites W1971591535 @default.
• W2017538797 cites W1972042391 @default.
• W2017538797 cites W1972113718 @default.
• W2017538797 cites W1973188998 @default.
• W2017538797 cites W1973444007 @default.
• W2017538797 cites W1973959152 @default.
• W2017538797 cites W1975280953 @default.
• W2017538797 cites W1976101063 @default.
• W2017538797 cites W1977915889 @default.
• W2017538797 cites W1977993870 @default.
• W2017538797 cites W1978865078 @default.
• W2017538797 cites W1978890358 @default.
• W2017538797 cites W1980338655 @default.
• W2017538797 cites W1980871365 @default.
• W2017538797 cites W1981565804 @default.
• W2017538797 cites W1981981746 @default.
• W2017538797 cites W1982298201 @default.
• W2017538797 cites W1982533921 @default.
• W2017538797 cites W1982675522 @default.
• W2017538797 cites W1982708091 @default.
• W2017538797 cites W1983022952 @default.
• W2017538797 cites W1983306533 @default.
• W2017538797 cites W1983724752 @default.
• W2017538797 cites W1983915872 @default.
• W2017538797 cites W1984112547 @default.
• W2017538797 cites W1984168496 @default.
• W2017538797 cites W1984817726 @default.
• W2017538797 cites W1986272649 @default.
• W2017538797 cites W1988057900 @default.
• W2017538797 cites W1988477534 @default.
• W2017538797 cites W1988534476 @default.
• W2017538797 cites W1989068748 @default.
• W2017538797 cites W1989662003 @default.
• W2017538797 cites W1989851109 @default.
• W2017538797 cites W1990390677 @default.
• W2017538797 cites W1990544580 @default.
• W2017538797 cites W1990922199 @default.
• W2017538797 cites W1991230641 @default.
• W2017538797 cites W1991386594 @default.
• W2017538797 cites W1991432128 @default.
• W2017538797 cites W1991476391 @default.
• W2017538797 cites W1994675107 @default.
• W2017538797 cites W1995704042 @default.
• W2017538797 cites W1996292143 @default.
• W2017538797 cites W1996319967 @default.
• W2017538797 cites W1996325119 @default.
• W2017538797 cites W1996904607 @default.
• W2017538797 cites W1996923779 @default.
• W2017538797 cites W1997753010 @default.
• W2017538797 cites W2000135589 @default.
• W2017538797 cites W2000209272 @default.
• W2017538797 cites W2000230039 @default.
• W2017538797 cites W2000739611 @default.
• W2017538797 cites W2000845178 @default.
• W2017538797 cites W2001185212 @default.
• W2017538797 cites W2002646435 @default.
• W2017538797 cites W2002744066 @default.
• W2017538797 cites W2003334359 @default.
• W2017538797 cites W2003387529 @default.
• W2017538797 cites W2003884044 @default.
• W2017538797 cites W2004850059 @default.
• W2017538797 cites W2005114112 @default.
• W2017538797 cites W2006231479 @default.
• W2017538797 cites W2006642291 @default.
• W2017538797 cites W2008041913 @default.
• W2017538797 cites W2009211072 @default.
• W2017538797 cites W2009556183 @default.
• W2017538797 cites W2011853698 @default.
• W2017538797 cites W2012473259 @default.
• W2017538797 cites W2013905807 @default.
• W2017538797 cites W2014604638 @default.
• W2017538797 cites W2014915327 @default.
• W2017538797 cites W2015096789 @default.
• W2017538797 cites W2015149685 @default.
• W2017538797 cites W2016525610 @default.
• W2017538797 cites W2016681879 @default.

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