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- W2017552048 abstract "Stimulation of excitatory neurons triggers the movement of calcium into dendritic spines and the build up of second messengers in the spine head, which, in turn, activates regulatory signalling cascades that underpin alterations in the strength of excitatory synapses. The level of signalling molecules in the spine head is therefore crucial for the induction of synaptic plasticity, and Bloodgood and Sabatini have now shown that the spine neck has a dynamic role as a diffusion barrier in regulating the movement of these molecules into and out of the spine head." @default.
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- W2017552048 date "2006-01-01" @default.
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- W2017552048 title "A barrier to diffusion" @default.
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- W2017552048 doi "https://doi.org/10.1038/nrn1831" @default.
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