FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017607856> ?p ?o ?g. }

• W2017607856 endingPage "176" @default.
• W2017607856 startingPage "172" @default.
• W2017607856 abstract "Summary The mechanism of disease progression in Hashimoto's thyroiditis (HT) is still unclear. Anti-thyroid peroxidase antibody (TPOAb), a diagnostic hallmark of HT, is principally of the immunoglobulin G (IgG) isotype, and it appears to be a response to thyroid injury. The aim of our study was to evaluate the distribution of IgG subclasses of TPOAb in sera from patients with HT with different thyroid functional status. Sera from 168 patients with newly diagnosed HT were collected and divided into three groups according to thyroid function: patients with hypothyroidism (n = 66), subclinical hypothyroidism (n = 60) and euthyroidism (n = 42). Antigen-specific enzyme-linked immunosorbent assay was used to detect the distribution of TPOAb IgG subclasses. The prevalence of TPOAb IgG subclasses in all patients’ sera with HT was IgG1 70·2%, IgG2 35·1%, IgG3 19·6% and IgG4 66·1% respectively. The prevalence of IgG2 in sera from patients with hypothyroidism (51·5%) was significantly higher than that of subclinical hypothyroidism (33·3%) (P &lt; 0·05), and the latter was also significantly higher than that of euthyroidism (11·9%) (P &lt; 0·05). The positive percentage of IgG2 subclass in sera from patients with hypothyroidism and subclinical hypothyroidism was significantly higher than that of euthyroidism (P &lt; 0·05), the prevalence and positive percentage of IgG4 subclass in sera from patients with hypothyroidism and subclinical hypothyroidism was significantly higher than that of euthyroidism respectively (P &lt; 0·05). The predominant TPOAb IgG subclasses in sera from patients with HT were IgG1 and IgG4. Patients with high levels of TPOAb IgG2, IgG4 subclasses might be at high risk of developing overt hypothyroidism." @default.
• W2017607856 created "2016-06-24" @default.
• W2017607856 creator A5023624619 @default.
• W2017607856 creator A5024852803 @default.
• W2017607856 creator A5031281766 @default.
• W2017607856 creator A5080082135 @default.
• W2017607856 creator A5087344550 @default.
• W2017607856 date "2008-09-05" @default.
• W2017607856 modified "2023-09-28" @default.
• W2017607856 title "Distribution of immunoglobulin G subclasses of anti-thyroid peroxidase antibody in sera from patients with Hashimoto's thyroiditis with different thyroid functional status" @default.
• W2017607856 cites W1914370328 @default.
• W2017607856 cites W1969482494 @default.
• W2017607856 cites W1973842455 @default.
• W2017607856 cites W2010499716 @default.
• W2017607856 cites W2032729180 @default.
• W2017607856 cites W2077977426 @default.
• W2017607856 cites W2086862391 @default.
• W2017607856 cites W2091805637 @default.
• W2017607856 cites W2092562610 @default.
• W2017607856 cites W2098125547 @default.
• W2017607856 cites W2104756061 @default.
• W2017607856 cites W2106833014 @default.
• W2017607856 cites W2133547068 @default.
• W2017607856 cites W2137141532 @default.
• W2017607856 cites W2142142226 @default.
• W2017607856 cites W2247483685 @default.
• W2017607856 cites W2314357784 @default.
• W2017607856 doi "https://doi.org/10.1111/j.1365-2249.2008.03756.x" @default.
• W2017607856 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2612718" @default.
• W2017607856 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18778360" @default.
• W2017607856 hasPublicationYear "2008" @default.
• W2017607856 type Work @default.
• W2017607856 sameAs 2017607856 @default.
• W2017607856 citedByCount "37" @default.
• W2017607856 countsByYear W20176078562013 @default.
• W2017607856 countsByYear W20176078562014 @default.
• W2017607856 countsByYear W20176078562015 @default.
• W2017607856 countsByYear W20176078562016 @default.
• W2017607856 countsByYear W20176078562017 @default.
• W2017607856 countsByYear W20176078562018 @default.
• W2017607856 countsByYear W20176078562019 @default.
• W2017607856 countsByYear W20176078562020 @default.
• W2017607856 countsByYear W20176078562021 @default.
• W2017607856 countsByYear W20176078562022 @default.
• W2017607856 crossrefType "journal-article" @default.
• W2017607856 hasAuthorship W2017607856A5023624619 @default.
• W2017607856 hasAuthorship W2017607856A5024852803 @default.
• W2017607856 hasAuthorship W2017607856A5031281766 @default.
• W2017607856 hasAuthorship W2017607856A5080082135 @default.
• W2017607856 hasAuthorship W2017607856A5087344550 @default.
• W2017607856 hasBestOaLocation W20176078562 @default.
• W2017607856 hasConcept C113280763 @default.
• W2017607856 hasConcept C126322002 @default.
• W2017607856 hasConcept C134018914 @default.
• W2017607856 hasConcept C159654299 @default.
• W2017607856 hasConcept C163764329 @default.
• W2017607856 hasConcept C180650514 @default.
• W2017607856 hasConcept C203014093 @default.
• W2017607856 hasConcept C2776194381 @default.
• W2017607856 hasConcept C2778696486 @default.
• W2017607856 hasConcept C2993291352 @default.
• W2017607856 hasConcept C50181227 @default.
• W2017607856 hasConcept C526584372 @default.
• W2017607856 hasConcept C71924100 @default.
• W2017607856 hasConcept C90924648 @default.
• W2017607856 hasConceptScore W2017607856C113280763 @default.
• W2017607856 hasConceptScore W2017607856C126322002 @default.
• W2017607856 hasConceptScore W2017607856C134018914 @default.
• W2017607856 hasConceptScore W2017607856C159654299 @default.
• W2017607856 hasConceptScore W2017607856C163764329 @default.
• W2017607856 hasConceptScore W2017607856C180650514 @default.
• W2017607856 hasConceptScore W2017607856C203014093 @default.
• W2017607856 hasConceptScore W2017607856C2776194381 @default.
• W2017607856 hasConceptScore W2017607856C2778696486 @default.
• W2017607856 hasConceptScore W2017607856C2993291352 @default.
• W2017607856 hasConceptScore W2017607856C50181227 @default.
• W2017607856 hasConceptScore W2017607856C526584372 @default.
• W2017607856 hasConceptScore W2017607856C71924100 @default.
• W2017607856 hasConceptScore W2017607856C90924648 @default.
• W2017607856 hasIssue "2" @default.
• W2017607856 hasLocation W20176078561 @default.
• W2017607856 hasLocation W20176078562 @default.
• W2017607856 hasLocation W20176078563 @default.
• W2017607856 hasOpenAccess W2017607856 @default.
• W2017607856 hasPrimaryLocation W20176078561 @default.
• W2017607856 hasRelatedWork W1582014088 @default.
• W2017607856 hasRelatedWork W2003573984 @default.
• W2017607856 hasRelatedWork W2017607856 @default.
• W2017607856 hasRelatedWork W2027918659 @default.
• W2017607856 hasRelatedWork W2029882570 @default.
• W2017607856 hasRelatedWork W2085668963 @default.
• W2017607856 hasRelatedWork W2098747404 @default.
• W2017607856 hasRelatedWork W2940817361 @default.
• W2017607856 hasRelatedWork W3023059945 @default.
• W2017607856 hasRelatedWork W4200587989 @default.
• W2017607856 hasVolume "154" @default.
• W2017607856 isParatext "false" @default.
• W2017607856 isRetracted "false" @default.

• next