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Matches in SemOpenAlex for { <https://semopenalex.org/work/W201761577> ?p ?o ?g. }

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• W201761577 abstract "To improve cytotoxicity of 10-deoxy-10-C-morpholinoethyl docetaxel analogues against various tumor cell lines including resistant cells expressing P-glycoprotein (P-gp), we modified the 7-hydroxyl group to hydrophobic groups (methoxy, deoxy, 6,7-olefin, alpha-F, 7-beta-8-beta-methano, fluoromethoxy). Among these analogues, the 7-methoxy analogue showed the strongest cytotoxicity. This analogue showed potent activity against B16 melanoma BL6 in vivo by oral administration." @default.
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• W201761577 date "2001-02-01" @default.
• W201761577 modified "2023-10-18" @default.
• W201761577 title "Orally active docetaxel analogue" @default.
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• W201761577 doi "https://doi.org/10.1016/s0960-894x(00)00682-x" @default.
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