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- W2017641799 abstract "1. Cultured mammalian cells which are in DNA synthesis incorporate 3H-thymidine into their chromosomal complement in less than 12 minute after addition of the tracer to the medium. 2. Although DNA synthetic rate in the culture as a whole is constant, the synthesis of DNA in the cell apparently does not occur at a linear rate during all of the 6 hour synthetic period. 3. Exclusive nucleolar labeling by 3H-thymidine was not observed, but occasional clustering of label around the nucleolus suggests some function in DNA metabolism. 4. DNA synthesis probably is occurring simultaneously in all the chromosomes of the HeLa cell during most of the 6 hour synthesis period, but the onset and termination of synthesis may vary among the chromosomes." @default.
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- W2017641799 title "Further studies on deoxyribonucleic acid metabolism in mammalian cell cultures" @default.
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- W2017641799 doi "https://doi.org/10.1016/0014-4827(60)90350-5" @default.
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