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- W2017649417 abstract "gamma-Decalactone (gamma-C10) is known to be highly toxic for the microorganims used for its production. In this work, three techniques were studied in order to overcome this toxicity during a bioconversion process using ricinoleic acid as precursor of the lactone: in situ trapping in oily phases, in porous hydrophobic sorbents and in beta-cyclodextrins. Oily phases added to the media (olive, Miglyol, tributyrin, and paraffin) had a protective effect on Sp. salmonicolor, and they improved the lactone production. beta-cyclodextrins, which have a hydrophobic cavity that can trap molecules such as gamma-C10, have been used to protect the yeasts. The results showed insufficient preservation of cell viability. Some sorbents (activated carbon and polystyrene-based sorbents) were successfully tested during bioconversion. In all cases viability exceeded the reference one. Nevertheless the aroma production was 30% lower than the reference. All of these solutions led to some enhancement of the cell viability during bioconversion of methyl ricinoleate to gamma-C10. For improvement of the lactone production, the oil trapping method seemed to be the best with the experimental conditions tested." @default.
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- W2017649417 date "1999-02-05" @default.
- W2017649417 modified "2023-10-13" @default.
- W2017649417 title "In Situ Detoxification of the Fermentation Medium during γ-Decalactone Production with the Yeast Sporidiobolus salmonicolor" @default.
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- W2017649417 doi "https://doi.org/10.1021/bp980113a" @default.
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