Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017652232> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2017652232 endingPage "4561" @default.
- W2017652232 startingPage "4557" @default.
- W2017652232 abstract "The effects of serotonin (5-HT), a well-known immunomodulator and neurotransmitter, on the ionic permeability of a pre-B lymphocyte cell line was investigated with the whole-cell patch-clamp technique. We found that physiological doses of this biogenic amine regulate a voltage-gated potassium channel by activating different subsets of receptors. More specifically, 5-HT induces in the recorded cells (i) increase in the maximum potassium conductance, which is due to activation of 5-HT1-like receptors, and (ii) acceleration of the inactivation process that is under the control of 5-HT3 receptors and, accordingly, is mimicked by the 5-HT3 agonist, 2-methyl-5-HT; involvement of those two distinct categories of receptors was demonstrated by using specific antagonists that block predominantly one or the other of these two actions. These two results show that hormones can affect lymphocyte physiology through modulation of their ionic conductances in a way that might help explain some of the diverse effects of 5-HT on neuronal cells." @default.
- W2017652232 created "2016-06-24" @default.
- W2017652232 creator A5039378309 @default.
- W2017652232 creator A5081422974 @default.
- W2017652232 date "1988-06-01" @default.
- W2017652232 modified "2023-09-27" @default.
- W2017652232 title "Dual effects of serotonin on a voltage-gated conductance in lymphocytes." @default.
- W2017652232 cites W1547358377 @default.
- W2017652232 cites W1959914161 @default.
- W2017652232 cites W1963911300 @default.
- W2017652232 cites W1981783120 @default.
- W2017652232 cites W1984304598 @default.
- W2017652232 cites W1989580086 @default.
- W2017652232 cites W1995604771 @default.
- W2017652232 cites W1998615691 @default.
- W2017652232 cites W2005395166 @default.
- W2017652232 cites W2025930377 @default.
- W2017652232 cites W2027200716 @default.
- W2017652232 cites W2031712341 @default.
- W2017652232 cites W2032498575 @default.
- W2017652232 cites W2033069160 @default.
- W2017652232 cites W2034961437 @default.
- W2017652232 cites W2036704251 @default.
- W2017652232 cites W2041694732 @default.
- W2017652232 cites W2071335648 @default.
- W2017652232 cites W2081772709 @default.
- W2017652232 cites W2084609395 @default.
- W2017652232 cites W2102126181 @default.
- W2017652232 cites W2104727590 @default.
- W2017652232 cites W2125469822 @default.
- W2017652232 cites W2173070011 @default.
- W2017652232 doi "https://doi.org/10.1073/pnas.85.12.4557" @default.
- W2017652232 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/280470" @default.
- W2017652232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3260036" @default.
- W2017652232 hasPublicationYear "1988" @default.
- W2017652232 type Work @default.
- W2017652232 sameAs 2017652232 @default.
- W2017652232 citedByCount "39" @default.
- W2017652232 countsByYear W20176522322020 @default.
- W2017652232 countsByYear W20176522322021 @default.
- W2017652232 crossrefType "journal-article" @default.
- W2017652232 hasAuthorship W2017652232A5039378309 @default.
- W2017652232 hasAuthorship W2017652232A5081422974 @default.
- W2017652232 hasBestOaLocation W20176522322 @default.
- W2017652232 hasConcept C12554922 @default.
- W2017652232 hasConcept C147944092 @default.
- W2017652232 hasConcept C156927020 @default.
- W2017652232 hasConcept C170493617 @default.
- W2017652232 hasConcept C185592680 @default.
- W2017652232 hasConcept C2775864247 @default.
- W2017652232 hasConcept C2776219046 @default.
- W2017652232 hasConcept C2778938600 @default.
- W2017652232 hasConcept C53910766 @default.
- W2017652232 hasConcept C55493867 @default.
- W2017652232 hasConcept C83743174 @default.
- W2017652232 hasConcept C86803240 @default.
- W2017652232 hasConcept C95444343 @default.
- W2017652232 hasConceptScore W2017652232C12554922 @default.
- W2017652232 hasConceptScore W2017652232C147944092 @default.
- W2017652232 hasConceptScore W2017652232C156927020 @default.
- W2017652232 hasConceptScore W2017652232C170493617 @default.
- W2017652232 hasConceptScore W2017652232C185592680 @default.
- W2017652232 hasConceptScore W2017652232C2775864247 @default.
- W2017652232 hasConceptScore W2017652232C2776219046 @default.
- W2017652232 hasConceptScore W2017652232C2778938600 @default.
- W2017652232 hasConceptScore W2017652232C53910766 @default.
- W2017652232 hasConceptScore W2017652232C55493867 @default.
- W2017652232 hasConceptScore W2017652232C83743174 @default.
- W2017652232 hasConceptScore W2017652232C86803240 @default.
- W2017652232 hasConceptScore W2017652232C95444343 @default.
- W2017652232 hasIssue "12" @default.
- W2017652232 hasLocation W20176522321 @default.
- W2017652232 hasLocation W20176522322 @default.
- W2017652232 hasLocation W20176522323 @default.
- W2017652232 hasLocation W20176522324 @default.
- W2017652232 hasOpenAccess W2017652232 @default.
- W2017652232 hasPrimaryLocation W20176522321 @default.
- W2017652232 hasRelatedWork W131282522 @default.
- W2017652232 hasRelatedWork W146028978 @default.
- W2017652232 hasRelatedWork W1509863809 @default.
- W2017652232 hasRelatedWork W2070339305 @default.
- W2017652232 hasRelatedWork W2072723883 @default.
- W2017652232 hasRelatedWork W2077435495 @default.
- W2017652232 hasRelatedWork W2078198153 @default.
- W2017652232 hasRelatedWork W2425952345 @default.
- W2017652232 hasRelatedWork W2467603323 @default.
- W2017652232 hasRelatedWork W946318013 @default.
- W2017652232 hasVolume "85" @default.
- W2017652232 isParatext "false" @default.
- W2017652232 isRetracted "false" @default.
- W2017652232 magId "2017652232" @default.
- W2017652232 workType "article" @default.