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- W2017662524 abstract "Acute myeloid leukaemia (AML) with the t(8;21)(q22;q22) is deemed to be a ‘good-risk’ disease. 396 patients with AML at diagnosis were screened for the presence of t(8;21) and AML1/ETO fusion transcripts by cytogenetic and RT-PCR techniques respectively. 32 cases of t(8;21) were detected, all of which were also PCR positive. A further 19 cases were detected at the molecular level, predominantly but not exclusively in M1 and M2 FAB types. Approximately 12% of all new cases of AML are estimated to have AML1/ETO fusion transcripts and it is suggested that molecular screening should be performed in all cases with the possible exception of the M3 FAB type." @default.
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- W2017662524 date "1997-12-01" @default.
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- W2017662524 title "Incidence of AML1/ETO fusion transcripts in patients entered into the MRC AML trials" @default.
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- W2017662524 doi "https://doi.org/10.1046/j.1365-2141.1997.4663270.x" @default.
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