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- W2017663577 abstract "To demonstrate the ultrasound findings and clinical outcome in a series of fetuses with echogenic kidneys. Prospective review of a series of 25 cases of echogenic fetal kidneys seen in a single academic center over a 2.5 year period. Cases were found on routine mid-trimester ultrasound. Kidneys were described as echogenic if they were brighter than liver parenchyma. None of the cases exhibited obvious cystic changes. Enlargement of the kidneys was noted in several cases. 11 of the 25 cases exhibited normalization of echogenicity during the course of gestation. Of those 11 cases, 8 were male and more likely to also have transient pelviectasis during gestation. Of the 14 cases with persistent echogenicity ± renal enlargement, only 4 were normal by imaging and function at the time of birth. Significant abnormalities identified in the remaining cases included 3 cases of autosomal recessive polycystic kidneys, 2 cases of Beckwith-Wiedemann, 1 case of cystic renal dysplasia, 2 cases of trisomy 13, and 1 case with a yet unspecified abnormality. 1 case remains undelivered. The wide spectrum of outcome in cases of echogenic fetal kidneys makes prediction of prognosis difficult. Preservation of normal renal architecture and size and normal amniotic fluid are important prognostic indicators. According to our series of echogenic fetal kidneys, there is about a 50% chance of resolution prior to birth. The higher preponderance of male gender with the associated pelviectasis may be causal in ‘false positive’ cases. Of cases with persistence of abnormal echogenicity ± renal enlargement throughout gestation, about 2/3 will have significant renal impairment, often with an associated genetic syndrome. Postnatal imaging and evaluation of renal function in order to determine appropriate follow-up is essential. A multidisciplinary approach to management including involvement of pediatric subspecialists and genetic counseling is recommended." @default.
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- W2017663577 date "2010-10-01" @default.
- W2017663577 modified "2023-10-18" @default.
- W2017663577 title "OP33.09: Echogenic kidneys in the fetus: correlation with postnatal outcome" @default.
- W2017663577 doi "https://doi.org/10.1002/uog.8242" @default.
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