FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017666089> ?p ?o ?g. }

• W2017666089 endingPage "130" @default.
• W2017666089 startingPage "118" @default.
• W2017666089 abstract "Clinical evidence suggests that administration of Hypericum perforatum (Hp) extracts containing the photo-activated hypericin compounds may cause fewer skin photosensitization reactions than administration of pure hypericin. This study was conducted to determine whether the phototoxicity of hypericin in HaCaT keratinocytes could be attenuated by H. perforatum extracts and constituents. Two extracts, when supplemented with 20 μM hypericin: (1) an ethanol re-extraction of residue following a chloroform extraction (denoted ethanol(-chloroform)) (3.35 μM hypericin and 124.0 μM total flavonoids); and (2) a chloroform extract (hypericin and flavonoids not detected), showed 25% and 50% (p < 0.0001) less phototoxicity than 20 μM hypericin alone. Two H. perforatum constituents, when supplemented with 20 μM hypericin: (1) 10 μM chlorogenic acid; and (2) 0.25 μM pyropheophorbide, exhibited 24% (p < 0.05) and 40% (p < 0.05) less phototoxicity than 20 μM hypericin alone. The peroxidation of arachidonic acid was assessed as a measure of oxidative damage by photo-activated hypericin, but this parameter of lipid peroxidation was not influenced by the extracts or constituents. However α-tocopherol, a known antioxidant also did not influence the amount of lipid peroxidation induced in this system. These observations indicate that hypericin combined with H. perforatum extracts or constituents may exert less phototoxicity than pure hypericin, but possibly not through a reduction in arachidonic acid peroxidation." @default.
• W2017666089 created "2016-06-24" @default.
• W2017666089 creator A5008659449 @default.
• W2017666089 creator A5030893916 @default.
• W2017666089 creator A5031991305 @default.
• W2017666089 creator A5054490875 @default.
• W2017666089 creator A5054990859 @default.
• W2017666089 creator A5090120915 @default.
• W2017666089 date "2006-11-01" @default.
• W2017666089 modified "2023-10-18" @default.
• W2017666089 title "Reduction in hypericin-induced phototoxicity by Hypericum perforatum extracts and pure compounds" @default.
• W2017666089 cites W1536041849 @default.
• W2017666089 cites W159741139 @default.
• W2017666089 cites W174715135 @default.
• W2017666089 cites W1890053134 @default.
• W2017666089 cites W1893901863 @default.
• W2017666089 cites W1968003196 @default.
• W2017666089 cites W1975419167 @default.
• W2017666089 cites W1978871608 @default.
• W2017666089 cites W1978961664 @default.
• W2017666089 cites W1980470010 @default.
• W2017666089 cites W1980709752 @default.
• W2017666089 cites W2001307965 @default.
• W2017666089 cites W2015417818 @default.
• W2017666089 cites W2025071869 @default.
• W2017666089 cites W2036009413 @default.
• W2017666089 cites W2036582783 @default.
• W2017666089 cites W2036972754 @default.
• W2017666089 cites W2043116958 @default.
• W2017666089 cites W2050197302 @default.
• W2017666089 cites W2051913494 @default.
• W2017666089 cites W2064474622 @default.
• W2017666089 cites W2071866695 @default.
• W2017666089 cites W2090176644 @default.
• W2017666089 cites W2095225769 @default.
• W2017666089 cites W2100863870 @default.
• W2017666089 cites W2101212222 @default.
• W2017666089 cites W2125760670 @default.
• W2017666089 cites W2153563295 @default.
• W2017666089 cites W2157244953 @default.
• W2017666089 cites W2165109132 @default.
• W2017666089 cites W3028438599 @default.
• W2017666089 cites W4245918130 @default.
• W2017666089 cites W4300884585 @default.
• W2017666089 doi "https://doi.org/10.1016/j.jphotobiol.2006.06.001" @default.
• W2017666089 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1618768" @default.
• W2017666089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16859921" @default.
• W2017666089 hasPublicationYear "2006" @default.
• W2017666089 type Work @default.
• W2017666089 sameAs 2017666089 @default.
• W2017666089 citedByCount "29" @default.
• W2017666089 countsByYear W20176660892012 @default.
• W2017666089 countsByYear W20176660892013 @default.
• W2017666089 countsByYear W20176660892014 @default.
• W2017666089 countsByYear W20176660892015 @default.
• W2017666089 countsByYear W20176660892017 @default.
• W2017666089 countsByYear W20176660892018 @default.
• W2017666089 countsByYear W20176660892020 @default.
• W2017666089 countsByYear W20176660892021 @default.
• W2017666089 countsByYear W20176660892022 @default.
• W2017666089 countsByYear W20176660892023 @default.
• W2017666089 crossrefType "journal-article" @default.
• W2017666089 hasAuthorship W2017666089A5008659449 @default.
• W2017666089 hasAuthorship W2017666089A5030893916 @default.
• W2017666089 hasAuthorship W2017666089A5031991305 @default.
• W2017666089 hasAuthorship W2017666089A5054490875 @default.
• W2017666089 hasAuthorship W2017666089A5054990859 @default.
• W2017666089 hasAuthorship W2017666089A5090120915 @default.
• W2017666089 hasBestOaLocation W20176660892 @default.
• W2017666089 hasConcept C181199279 @default.
• W2017666089 hasConcept C185592680 @default.
• W2017666089 hasConcept C202751555 @default.
• W2017666089 hasConcept C20639190 @default.
• W2017666089 hasConcept C2776651039 @default.
• W2017666089 hasConcept C2778004101 @default.
• W2017666089 hasConcept C2778078955 @default.
• W2017666089 hasConcept C2778432610 @default.
• W2017666089 hasConcept C2780117898 @default.
• W2017666089 hasConcept C2780829032 @default.
• W2017666089 hasConcept C2781144210 @default.
• W2017666089 hasConcept C43617362 @default.
• W2017666089 hasConcept C55493867 @default.
• W2017666089 hasConcept C71924100 @default.
• W2017666089 hasConcept C98274493 @default.
• W2017666089 hasConceptScore W2017666089C181199279 @default.
• W2017666089 hasConceptScore W2017666089C185592680 @default.
• W2017666089 hasConceptScore W2017666089C202751555 @default.
• W2017666089 hasConceptScore W2017666089C20639190 @default.
• W2017666089 hasConceptScore W2017666089C2776651039 @default.
• W2017666089 hasConceptScore W2017666089C2778004101 @default.
• W2017666089 hasConceptScore W2017666089C2778078955 @default.
• W2017666089 hasConceptScore W2017666089C2778432610 @default.
• W2017666089 hasConceptScore W2017666089C2780117898 @default.
• W2017666089 hasConceptScore W2017666089C2780829032 @default.
• W2017666089 hasConceptScore W2017666089C2781144210 @default.
• W2017666089 hasConceptScore W2017666089C43617362 @default.
• W2017666089 hasConceptScore W2017666089C55493867 @default.
• W2017666089 hasConceptScore W2017666089C71924100 @default.

• next