FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017670466> ?p ?o ?g. }

• W2017670466 endingPage "205" @default.
• W2017670466 startingPage "201" @default.
• W2017670466 abstract "Presentation of antigenic peptides by major histocompatibility complex (MHC) class I molecules requires MHC-encoded molecules of the adenosine triphosphate binding cassette (ABC) family. Defects in these proteins represent a potential risk, since they are essential links in the machinery of T cell-mediated surveillance which continuously scrutinizes peptide samples of cellular proteins. Nevertheless, transfection of the mouse lymphoma mutant RMA-S with the rat ABC gene mtp2a (homologue to mouse HAM2 and human RING11), commonly termed TAP-2 genes, led to a marked increase in tumor outgrowth potential in vivo. This occurred despite restored antigen presentation and sensitivity to cytotoxic T lymphocytes, and was found to be due to escape from natural killer (NK) cell-mediated rejection. It has previously been proposed that adequate expression of self-MHC class I is one important mechanism to avoid elimination by NK cells. Our data argue that a defect in the machinery responsible for processing and loading of peptides into MHC class I molecules is sufficient to render cells sensitive to elimination by NK cells. The latter thus appear to function as a surveillance of the peptide surveillance machinery." @default.
• W2017670466 created "2016-06-24" @default.
• W2017670466 creator A5001117022 @default.
• W2017670466 creator A5002674606 @default.
• W2017670466 creator A5059703200 @default.
• W2017670466 creator A5065543859 @default.
• W2017670466 creator A5065806867 @default.
• W2017670466 creator A5072274529 @default.
• W2017670466 date "1993-01-01" @default.
• W2017670466 modified "2023-10-03" @default.
• W2017670466 title "Tumorigenicity conferred to lymphoma mutant by major histocompatibility complex-encoded transporter gene." @default.
• W2017670466 cites W1501455692 @default.
• W2017670466 cites W1537406409 @default.
• W2017670466 cites W1578442064 @default.
• W2017670466 cites W1584719350 @default.
• W2017670466 cites W1972450532 @default.
• W2017670466 cites W1980036435 @default.
• W2017670466 cites W1990806106 @default.
• W2017670466 cites W1993319836 @default.
• W2017670466 cites W1994435196 @default.
• W2017670466 cites W1996567630 @default.
• W2017670466 cites W2000583744 @default.
• W2017670466 cites W2003828446 @default.
• W2017670466 cites W2006629564 @default.
• W2017670466 cites W2007166746 @default.
• W2017670466 cites W2020846586 @default.
• W2017670466 cites W2034712661 @default.
• W2017670466 cites W2035891785 @default.
• W2017670466 cites W2036052491 @default.
• W2017670466 cites W2045245707 @default.
• W2017670466 cites W2049773295 @default.
• W2017670466 cites W2053093244 @default.
• W2017670466 cites W2055034075 @default.
• W2017670466 cites W2068379381 @default.
• W2017670466 cites W2082173837 @default.
• W2017670466 cites W2083988731 @default.
• W2017670466 cites W2084093106 @default.
• W2017670466 cites W2084555605 @default.
• W2017670466 cites W2085450869 @default.
• W2017670466 cites W2088513299 @default.
• W2017670466 cites W2093539004 @default.
• W2017670466 cites W2095171806 @default.
• W2017670466 cites W2109034317 @default.
• W2017670466 cites W2118376550 @default.
• W2017670466 cites W2149810322 @default.
• W2017670466 doi "https://doi.org/10.1084/jem.177.1.201" @default.
• W2017670466 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2190880" @default.
• W2017670466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8418201" @default.
• W2017670466 hasPublicationYear "1993" @default.
• W2017670466 type Work @default.
• W2017670466 sameAs 2017670466 @default.
• W2017670466 citedByCount "64" @default.
• W2017670466 countsByYear W20176704662012 @default.
• W2017670466 countsByYear W20176704662013 @default.
• W2017670466 countsByYear W20176704662014 @default.
• W2017670466 countsByYear W20176704662016 @default.
• W2017670466 countsByYear W20176704662017 @default.
• W2017670466 countsByYear W20176704662018 @default.
• W2017670466 countsByYear W20176704662020 @default.
• W2017670466 countsByYear W20176704662023 @default.
• W2017670466 crossrefType "journal-article" @default.
• W2017670466 hasAuthorship W2017670466A5001117022 @default.
• W2017670466 hasAuthorship W2017670466A5002674606 @default.
• W2017670466 hasAuthorship W2017670466A5059703200 @default.
• W2017670466 hasAuthorship W2017670466A5065543859 @default.
• W2017670466 hasAuthorship W2017670466A5065806867 @default.
• W2017670466 hasAuthorship W2017670466A5072274529 @default.
• W2017670466 hasBestOaLocation W20176704661 @default.
• W2017670466 hasConcept C104317684 @default.
• W2017670466 hasConcept C108249834 @default.
• W2017670466 hasConcept C147483822 @default.
• W2017670466 hasConcept C153911025 @default.
• W2017670466 hasConcept C154317977 @default.
• W2017670466 hasConcept C170627219 @default.
• W2017670466 hasConcept C202751555 @default.
• W2017670466 hasConcept C207936829 @default.
• W2017670466 hasConcept C22845430 @default.
• W2017670466 hasConcept C37386791 @default.
• W2017670466 hasConcept C54009773 @default.
• W2017670466 hasConcept C54355233 @default.
• W2017670466 hasConcept C67662055 @default.
• W2017670466 hasConcept C83464605 @default.
• W2017670466 hasConcept C86803240 @default.
• W2017670466 hasConcept C95444343 @default.
• W2017670466 hasConceptScore W2017670466C104317684 @default.
• W2017670466 hasConceptScore W2017670466C108249834 @default.
• W2017670466 hasConceptScore W2017670466C147483822 @default.
• W2017670466 hasConceptScore W2017670466C153911025 @default.
• W2017670466 hasConceptScore W2017670466C154317977 @default.
• W2017670466 hasConceptScore W2017670466C170627219 @default.
• W2017670466 hasConceptScore W2017670466C202751555 @default.
• W2017670466 hasConceptScore W2017670466C207936829 @default.
• W2017670466 hasConceptScore W2017670466C22845430 @default.
• W2017670466 hasConceptScore W2017670466C37386791 @default.
• W2017670466 hasConceptScore W2017670466C54009773 @default.
• W2017670466 hasConceptScore W2017670466C54355233 @default.
• W2017670466 hasConceptScore W2017670466C67662055 @default.
• W2017670466 hasConceptScore W2017670466C83464605 @default.

• next