FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017671346> ?p ?o ?g. }

• W2017671346 endingPage "e0122346" @default.
• W2017671346 startingPage "e0122346" @default.
• W2017671346 abstract "Introduction Children with hereditary neuromuscular diseases (NMDs) are at a high risk of morbidity and mortality related to respiratory failure. The use of home mechanical ventilation (HMV) has saved the lives of many children with NMD but, due to a lack of studies, dependable guidelines are not available. We drew upon our experience to compare the various underlying NMDs and to evaluate HMV with regard to respiratory morbidity, the proper indications and timing for its use, and to develop a policy to improve the quality of home noninvasive ventilation (NIV). Methods We retrospectively analyzed the medical records of 57 children with childhood-onset hereditary NMDs in whom HMV was initiated between January 2000 and May 2013 at Seoul National University Children's Hospital. The degree of respiratory morbidity was estimated by the frequency and duration of hospitalizations caused by respiratory distress. Results The most common NMD was spinal muscular atrophy (SMA, n = 33). Emergent mechanical ventilation was initiated in 44% of the patients before the confirmed diagnosis, and the indicators of pre-HMV respiratory morbidity (e.g., extubation trials, hypoxia, hospitalizations, and intensive care unit stay) were greater in these patients than in others. The proportion of post-HMV hospitalizations (range, 0.00−0.52; median, 0.01) was lower than that of pre-HMV hospitalizations (0.02−1.00; 0.99) (P < 0.001). Eight patients were able to maintain home NIV. The main causes of NIV failure were air leakage and a large amount of airway secretions. Conclusions The application of HMV helped reduce respiratory morbidity in children with childhood-onset hereditary NMD. Patients with SMA type I can benefit from an early diagnosis and the timely application of HMV. The choice between invasive and noninvasive HMV should be based on the patient’s age and NIV trial tolerance. Systematic follow-up guidelines provided by a multidisciplinary team are needed." @default.
• W2017671346 created "2016-06-24" @default.
• W2017671346 creator A5006269901 @default.
• W2017671346 creator A5018921521 @default.
• W2017671346 creator A5061232003 @default.
• W2017671346 creator A5078124168 @default.
• W2017671346 creator A5078328601 @default.
• W2017671346 creator A5086940052 @default.
• W2017671346 creator A5090794012 @default.
• W2017671346 date "2015-03-30" @default.
• W2017671346 modified "2023-09-25" @default.
• W2017671346 title "Home Mechanical Ventilation in Childhood-Onset Hereditary Neuromuscular Diseases: 13 Years’ Experience at a Single Center in Korea" @default.
• W2017671346 cites W132180646 @default.
• W2017671346 cites W1928247635 @default.
• W2017671346 cites W1965829588 @default.
• W2017671346 cites W1983877956 @default.
• W2017671346 cites W1992007549 @default.
• W2017671346 cites W2011093617 @default.
• W2017671346 cites W2014258610 @default.
• W2017671346 cites W2015861576 @default.
• W2017671346 cites W2021186393 @default.
• W2017671346 cites W2022110829 @default.
• W2017671346 cites W2024288480 @default.
• W2017671346 cites W2035683378 @default.
• W2017671346 cites W2041644833 @default.
• W2017671346 cites W2043369340 @default.
• W2017671346 cites W2053508833 @default.
• W2017671346 cites W2056036292 @default.
• W2017671346 cites W2058661653 @default.
• W2017671346 cites W2063756800 @default.
• W2017671346 cites W2064671494 @default.
• W2017671346 cites W2071898744 @default.
• W2017671346 cites W2078804386 @default.
• W2017671346 cites W2084671078 @default.
• W2017671346 cites W2085187220 @default.
• W2017671346 cites W2090903753 @default.
• W2017671346 cites W2091323685 @default.
• W2017671346 cites W2091344298 @default.
• W2017671346 cites W2091376380 @default.
• W2017671346 cites W2098275313 @default.
• W2017671346 cites W2098529946 @default.
• W2017671346 cites W2116764859 @default.
• W2017671346 cites W2119820612 @default.
• W2017671346 cites W2121807826 @default.
• W2017671346 cites W2133561625 @default.
• W2017671346 cites W2143197369 @default.
• W2017671346 cites W2163061912 @default.
• W2017671346 cites W2343394135 @default.
• W2017671346 cites W4240674940 @default.
• W2017671346 cites W4252352538 @default.
• W2017671346 cites W4252955468 @default.
• W2017671346 doi "https://doi.org/10.1371/journal.pone.0122346" @default.
• W2017671346 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4379105" @default.
• W2017671346 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25822836" @default.
• W2017671346 hasPublicationYear "2015" @default.
• W2017671346 type Work @default.
• W2017671346 sameAs 2017671346 @default.
• W2017671346 citedByCount "13" @default.
• W2017671346 countsByYear W20176713462016 @default.
• W2017671346 countsByYear W20176713462017 @default.
• W2017671346 countsByYear W20176713462018 @default.
• W2017671346 countsByYear W20176713462019 @default.
• W2017671346 countsByYear W20176713462020 @default.
• W2017671346 countsByYear W20176713462021 @default.
• W2017671346 countsByYear W20176713462022 @default.
• W2017671346 crossrefType "journal-article" @default.
• W2017671346 hasAuthorship W2017671346A5006269901 @default.
• W2017671346 hasAuthorship W2017671346A5018921521 @default.
• W2017671346 hasAuthorship W2017671346A5061232003 @default.
• W2017671346 hasAuthorship W2017671346A5078124168 @default.
• W2017671346 hasAuthorship W2017671346A5078328601 @default.
• W2017671346 hasAuthorship W2017671346A5086940052 @default.
• W2017671346 hasAuthorship W2017671346A5090794012 @default.
• W2017671346 hasBestOaLocation W20176713461 @default.
• W2017671346 hasConcept C126322002 @default.
• W2017671346 hasConcept C127413603 @default.
• W2017671346 hasConcept C141071460 @default.
• W2017671346 hasConcept C141983124 @default.
• W2017671346 hasConcept C177713679 @default.
• W2017671346 hasConcept C187212893 @default.
• W2017671346 hasConcept C194828623 @default.
• W2017671346 hasConcept C200457457 @default.
• W2017671346 hasConcept C2776356578 @default.
• W2017671346 hasConcept C2776888751 @default.
• W2017671346 hasConcept C2777080012 @default.
• W2017671346 hasConcept C2778558090 @default.
• W2017671346 hasConcept C2779134260 @default.
• W2017671346 hasConcept C71924100 @default.
• W2017671346 hasConcept C78519656 @default.
• W2017671346 hasConceptScore W2017671346C126322002 @default.
• W2017671346 hasConceptScore W2017671346C127413603 @default.
• W2017671346 hasConceptScore W2017671346C141071460 @default.
• W2017671346 hasConceptScore W2017671346C141983124 @default.
• W2017671346 hasConceptScore W2017671346C177713679 @default.
• W2017671346 hasConceptScore W2017671346C187212893 @default.
• W2017671346 hasConceptScore W2017671346C194828623 @default.
• W2017671346 hasConceptScore W2017671346C200457457 @default.
• W2017671346 hasConceptScore W2017671346C2776356578 @default.

• next