Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017679385> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2017679385 endingPage "353" @default.
- W2017679385 startingPage "331" @default.
- W2017679385 abstract "Epimedium pubescens Maxim. and Epimedium koreanum Nakai. are two common and confused species of Herba Epimedii in Chinese Pharmacopoeia 2010 edition. Different species and growing conditions lead to chemical differences between the two species which may result in the improper clinical usage. In this work, a new method based on rapid-resolution liquid chromatography combined with time-of-flight mass spectrometry (RRLC/TOFMS) has been developed for identification and differentiation of major flavonoids in two kinds of Epimedium extract and rat plasma. The compounds were identified effectively based on the accurate extract masses and formulae acquired by RRLC/TOFMS. The fragmentation rules deduced by collision-induced dissociation (CID) were successfully implemented in distinguishing some of the isomers, further validating the results. By using the combined analytical techniques, a total of 40 major flavonoids in extracts of two kinds of Epimedium were identified within 30 min, including 31 common components and 9 characteristic components. After oral administration, three prototype compounds in rat plasma were detected by comparing the constituents measured in vitro with those in vivo, and five metabolites were identified by contrasting the fragmentation rules. The identification and structural elucidation of the chemical constituents provided essential data for further pharmacological and clinical studies on different species of Epimedium." @default.
- W2017679385 created "2016-06-24" @default.
- W2017679385 creator A5023693660 @default.
- W2017679385 creator A5024638260 @default.
- W2017679385 creator A5048936963 @default.
- W2017679385 creator A5056913078 @default.
- W2017679385 creator A5070315010 @default.
- W2017679385 creator A5076439768 @default.
- W2017679385 creator A5088165302 @default.
- W2017679385 date "2015-06-01" @default.
- W2017679385 modified "2023-09-27" @default.
- W2017679385 title "Identification and differentiation of major flavonoids in two kinds ofEpimediumextracts and rat plasma by rapid-resolution liquid chromatography combined with time-of-flight mass spectrometry" @default.
- W2017679385 cites W1506097358 @default.
- W2017679385 cites W1971731246 @default.
- W2017679385 cites W1978476336 @default.
- W2017679385 cites W1996208332 @default.
- W2017679385 cites W2032050052 @default.
- W2017679385 cites W2038891871 @default.
- W2017679385 cites W2043620340 @default.
- W2017679385 cites W2058011126 @default.
- W2017679385 cites W2067372701 @default.
- W2017679385 cites W2067409923 @default.
- W2017679385 cites W2077280776 @default.
- W2017679385 cites W2077907404 @default.
- W2017679385 cites W2088790877 @default.
- W2017679385 cites W2089708715 @default.
- W2017679385 cites W2089880510 @default.
- W2017679385 cites W2093252399 @default.
- W2017679385 cites W2147844742 @default.
- W2017679385 cites W2161287092 @default.
- W2017679385 cites W2171953746 @default.
- W2017679385 doi "https://doi.org/10.1556/achrom.27.2015.2.10" @default.
- W2017679385 hasPublicationYear "2015" @default.
- W2017679385 type Work @default.
- W2017679385 sameAs 2017679385 @default.
- W2017679385 citedByCount "0" @default.
- W2017679385 crossrefType "journal-article" @default.
- W2017679385 hasAuthorship W2017679385A5023693660 @default.
- W2017679385 hasAuthorship W2017679385A5024638260 @default.
- W2017679385 hasAuthorship W2017679385A5048936963 @default.
- W2017679385 hasAuthorship W2017679385A5056913078 @default.
- W2017679385 hasAuthorship W2017679385A5070315010 @default.
- W2017679385 hasAuthorship W2017679385A5076439768 @default.
- W2017679385 hasAuthorship W2017679385A5088165302 @default.
- W2017679385 hasBestOaLocation W20176793851 @default.
- W2017679385 hasConcept C111919701 @default.
- W2017679385 hasConcept C138268822 @default.
- W2017679385 hasConcept C154945302 @default.
- W2017679385 hasConcept C162356407 @default.
- W2017679385 hasConcept C185592680 @default.
- W2017679385 hasConcept C191015642 @default.
- W2017679385 hasConcept C2779824472 @default.
- W2017679385 hasConcept C2781393221 @default.
- W2017679385 hasConcept C2991655182 @default.
- W2017679385 hasConcept C31827203 @default.
- W2017679385 hasConcept C41008148 @default.
- W2017679385 hasConcept C43617362 @default.
- W2017679385 hasConcept C556039675 @default.
- W2017679385 hasConcept C71924100 @default.
- W2017679385 hasConceptScore W2017679385C111919701 @default.
- W2017679385 hasConceptScore W2017679385C138268822 @default.
- W2017679385 hasConceptScore W2017679385C154945302 @default.
- W2017679385 hasConceptScore W2017679385C162356407 @default.
- W2017679385 hasConceptScore W2017679385C185592680 @default.
- W2017679385 hasConceptScore W2017679385C191015642 @default.
- W2017679385 hasConceptScore W2017679385C2779824472 @default.
- W2017679385 hasConceptScore W2017679385C2781393221 @default.
- W2017679385 hasConceptScore W2017679385C2991655182 @default.
- W2017679385 hasConceptScore W2017679385C31827203 @default.
- W2017679385 hasConceptScore W2017679385C41008148 @default.
- W2017679385 hasConceptScore W2017679385C43617362 @default.
- W2017679385 hasConceptScore W2017679385C556039675 @default.
- W2017679385 hasConceptScore W2017679385C71924100 @default.
- W2017679385 hasIssue "2" @default.
- W2017679385 hasLocation W20176793851 @default.
- W2017679385 hasOpenAccess W2017679385 @default.
- W2017679385 hasPrimaryLocation W20176793851 @default.
- W2017679385 hasRelatedWork W1969559554 @default.
- W2017679385 hasRelatedWork W1997103078 @default.
- W2017679385 hasRelatedWork W2014605936 @default.
- W2017679385 hasRelatedWork W2018070089 @default.
- W2017679385 hasRelatedWork W2029727067 @default.
- W2017679385 hasRelatedWork W2031426814 @default.
- W2017679385 hasRelatedWork W2033184238 @default.
- W2017679385 hasRelatedWork W2035971591 @default.
- W2017679385 hasRelatedWork W2085064906 @default.
- W2017679385 hasRelatedWork W2346859668 @default.
- W2017679385 hasVolume "27" @default.
- W2017679385 isParatext "false" @default.
- W2017679385 isRetracted "false" @default.
- W2017679385 magId "2017679385" @default.
- W2017679385 workType "article" @default.