Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017680617> ?p ?o ?g. }
- W2017680617 endingPage "252" @default.
- W2017680617 startingPage "242" @default.
- W2017680617 abstract "AMPA receptors have been identified in different populations of presynaptic terminals and found to be involved in the modulation of neurotransmitter release. The mechanisms that govern the expression of presynaptic AMPA receptors are not known. One possibility is that pre- and postsynaptic AMPA receptors are regulated according to the same principles. To address this hypothesis we investigated whether protein interacting with C kinase 1 (PICK1), known to interact with AMPA receptors postsynaptically, also is expressed presynaptically, together with AMPA receptors. Subfractionation and high-resolution immunogold analyses of the rat hippocampus revealed that GluR2 and PICK1 are enriched postsynaptically, but also in presynaptic membrane compartments, including the active zone and vesicular membranes. PICK1 and GluR2 are associated with the same vesicles, which are immunopositive also for synaptophysin and vesicle-associated membrane protein 2. Based on what is known about the function of PICK1 postsynaptically, the present data suggest that PICK1 is involved in the regulation of presynaptic AMPA receptor trafficking and in determining the size of the AMPA receptor pool that modulates presynaptic glutamate release." @default.
- W2017680617 created "2016-06-24" @default.
- W2017680617 creator A5013391824 @default.
- W2017680617 creator A5020293386 @default.
- W2017680617 creator A5023809102 @default.
- W2017680617 creator A5031615076 @default.
- W2017680617 creator A5054939494 @default.
- W2017680617 creator A5070110158 @default.
- W2017680617 creator A5078373679 @default.
- W2017680617 creator A5080681424 @default.
- W2017680617 creator A5081453717 @default.
- W2017680617 creator A5087096006 @default.
- W2017680617 date "2009-01-01" @default.
- W2017680617 modified "2023-10-17" @default.
- W2017680617 title "Protein interacting with C kinase 1 (PICK1) and GluR2 are associated with presynaptic plasma membrane and vesicles in hippocampal excitatory synapses" @default.
- W2017680617 cites W1535585371 @default.
- W2017680617 cites W1545709084 @default.
- W2017680617 cites W1548600249 @default.
- W2017680617 cites W1562693316 @default.
- W2017680617 cites W1597908762 @default.
- W2017680617 cites W1685129917 @default.
- W2017680617 cites W1929828037 @default.
- W2017680617 cites W1963923544 @default.
- W2017680617 cites W1964708473 @default.
- W2017680617 cites W1965982903 @default.
- W2017680617 cites W1978605718 @default.
- W2017680617 cites W1992756781 @default.
- W2017680617 cites W1993931258 @default.
- W2017680617 cites W1996208391 @default.
- W2017680617 cites W2001041036 @default.
- W2017680617 cites W2006108102 @default.
- W2017680617 cites W2009071652 @default.
- W2017680617 cites W2014045979 @default.
- W2017680617 cites W2021462093 @default.
- W2017680617 cites W2032846064 @default.
- W2017680617 cites W2038492152 @default.
- W2017680617 cites W2056817409 @default.
- W2017680617 cites W2061204783 @default.
- W2017680617 cites W2063959590 @default.
- W2017680617 cites W2064491371 @default.
- W2017680617 cites W2067887349 @default.
- W2017680617 cites W2076636373 @default.
- W2017680617 cites W2090677095 @default.
- W2017680617 cites W2105676590 @default.
- W2017680617 cites W2106042714 @default.
- W2017680617 cites W2108586733 @default.
- W2017680617 cites W2125437891 @default.
- W2017680617 cites W2138924208 @default.
- W2017680617 cites W2140899588 @default.
- W2017680617 cites W2141450570 @default.
- W2017680617 cites W2149280434 @default.
- W2017680617 cites W2160483038 @default.
- W2017680617 cites W2161442189 @default.
- W2017680617 cites W2165278449 @default.
- W2017680617 cites W2169578249 @default.
- W2017680617 doi "https://doi.org/10.1016/j.neuroscience.2008.11.029" @default.
- W2017680617 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19071197" @default.
- W2017680617 hasPublicationYear "2009" @default.
- W2017680617 type Work @default.
- W2017680617 sameAs 2017680617 @default.
- W2017680617 citedByCount "29" @default.
- W2017680617 countsByYear W20176806172012 @default.
- W2017680617 countsByYear W20176806172013 @default.
- W2017680617 countsByYear W20176806172015 @default.
- W2017680617 countsByYear W20176806172016 @default.
- W2017680617 countsByYear W20176806172017 @default.
- W2017680617 countsByYear W20176806172018 @default.
- W2017680617 countsByYear W20176806172019 @default.
- W2017680617 countsByYear W20176806172020 @default.
- W2017680617 countsByYear W20176806172021 @default.
- W2017680617 countsByYear W20176806172022 @default.
- W2017680617 crossrefType "journal-article" @default.
- W2017680617 hasAuthorship W2017680617A5013391824 @default.
- W2017680617 hasAuthorship W2017680617A5020293386 @default.
- W2017680617 hasAuthorship W2017680617A5023809102 @default.
- W2017680617 hasAuthorship W2017680617A5031615076 @default.
- W2017680617 hasAuthorship W2017680617A5054939494 @default.
- W2017680617 hasAuthorship W2017680617A5070110158 @default.
- W2017680617 hasAuthorship W2017680617A5078373679 @default.
- W2017680617 hasAuthorship W2017680617A5080681424 @default.
- W2017680617 hasAuthorship W2017680617A5081453717 @default.
- W2017680617 hasAuthorship W2017680617A5087096006 @default.
- W2017680617 hasConcept C112592302 @default.
- W2017680617 hasConcept C130316041 @default.
- W2017680617 hasConcept C148785051 @default.
- W2017680617 hasConcept C154559735 @default.
- W2017680617 hasConcept C160268369 @default.
- W2017680617 hasConcept C169760540 @default.
- W2017680617 hasConcept C170493617 @default.
- W2017680617 hasConcept C17077164 @default.
- W2017680617 hasConcept C185592680 @default.
- W2017680617 hasConcept C187541742 @default.
- W2017680617 hasConcept C189184402 @default.
- W2017680617 hasConcept C197341189 @default.
- W2017680617 hasConcept C41625074 @default.
- W2017680617 hasConcept C55493867 @default.
- W2017680617 hasConcept C61174792 @default.
- W2017680617 hasConcept C73009533 @default.