FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017682357> ?p ?o ?g. }

• W2017682357 endingPage "306" @default.
• W2017682357 startingPage "299" @default.
• W2017682357 abstract "This study investigate the expression of the mitogen-activated protein kinases (MAPKs) in normal prostate, benign prostatic hyperplasia (BPH), and prostatic cancer (PC), and also the possible relationship between the activity of these MAPKs and the apoptosis/proliferation index. Immunochemical techniques were carried out using 2 mouse monoclonal antibodies against human extracellular signal-regulated protein kinase (ERK) and Jun N-terminal kinase (JNK), and 1 goat polyclonal antibody against mouse p38. To compare the results obtained in the 3 specimens, the average percentages of both epithelial and stromal immunostained cells were calculated on immunostained sections. For each of the 3 kinases studied, the percentage of immunostained stromal cells did not change with prostatic alterations. For both ERK and p38, the percentage of immunostained epithelial cells increased significantly in BPH and even more so in PC. For JNK, the percentage of immunostained epithelial cells increased significantly only in PC. These results suggest that ERK could be involved in the elevated proliferation indexes reported in BPH and PC, whereas p38 might contribute to the increased apoptotic index reported in PC. The most probable action of JNK in PC would be cell proliferation stimulation. Overexpression of MAPKs, involved in the development of prostatic hyperplasia and neoplasia, might be secondary to the overexpression of several growth factors." @default.
• W2017682357 created "2016-06-24" @default.
• W2017682357 creator A5003215527 @default.
• W2017682357 creator A5012922484 @default.
• W2017682357 creator A5063024127 @default.
• W2017682357 creator A5068691936 @default.
• W2017682357 creator A5079298859 @default.
• W2017682357 creator A5088768411 @default.
• W2017682357 date "2002-03-01" @default.
• W2017682357 modified "2023-10-16" @default.
• W2017682357 title "Regulation of proliferation/apoptosis equilibrium by mitogen-activated protein kinases in normal, hyperplastic, and carcinomatous human prostate" @default.
• W2017682357 cites W1964146094 @default.
• W2017682357 cites W1964280812 @default.
• W2017682357 cites W1967683406 @default.
• W2017682357 cites W1970786059 @default.
• W2017682357 cites W1973040631 @default.
• W2017682357 cites W1980360982 @default.
• W2017682357 cites W1983214899 @default.
• W2017682357 cites W1986570146 @default.
• W2017682357 cites W2005010706 @default.
• W2017682357 cites W2014862668 @default.
• W2017682357 cites W2032582358 @default.
• W2017682357 cites W2038447145 @default.
• W2017682357 cites W2077628380 @default.
• W2017682357 cites W2085482333 @default.
• W2017682357 cites W2087172814 @default.
• W2017682357 cites W2095152292 @default.
• W2017682357 cites W2136046634 @default.
• W2017682357 cites W2150097377 @default.
• W2017682357 cites W2154652969 @default.
• W2017682357 cites W2159759132 @default.
• W2017682357 cites W2182204372 @default.
• W2017682357 cites W2328985298 @default.
• W2017682357 cites W2411414558 @default.
• W2017682357 cites W2412984143 @default.
• W2017682357 cites W2475324104 @default.
• W2017682357 cites W2499387497 @default.
• W2017682357 cites W4301428904 @default.
• W2017682357 doi "https://doi.org/10.1053/hupa.2002.32227" @default.
• W2017682357 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11979370" @default.
• W2017682357 hasPublicationYear "2002" @default.
• W2017682357 type Work @default.
• W2017682357 sameAs 2017682357 @default.
• W2017682357 citedByCount "73" @default.
• W2017682357 countsByYear W20176823572012 @default.
• W2017682357 countsByYear W20176823572013 @default.
• W2017682357 countsByYear W20176823572014 @default.
• W2017682357 countsByYear W20176823572015 @default.
• W2017682357 countsByYear W20176823572016 @default.
• W2017682357 countsByYear W20176823572017 @default.
• W2017682357 countsByYear W20176823572018 @default.
• W2017682357 countsByYear W20176823572019 @default.
• W2017682357 countsByYear W20176823572021 @default.
• W2017682357 countsByYear W20176823572022 @default.
• W2017682357 crossrefType "journal-article" @default.
• W2017682357 hasAuthorship W2017682357A5003215527 @default.
• W2017682357 hasAuthorship W2017682357A5012922484 @default.
• W2017682357 hasAuthorship W2017682357A5063024127 @default.
• W2017682357 hasAuthorship W2017682357A5068691936 @default.
• W2017682357 hasAuthorship W2017682357A5079298859 @default.
• W2017682357 hasAuthorship W2017682357A5088768411 @default.
• W2017682357 hasConcept C121608353 @default.
• W2017682357 hasConcept C126322002 @default.
• W2017682357 hasConcept C132149769 @default.
• W2017682357 hasConcept C142724271 @default.
• W2017682357 hasConcept C16930146 @default.
• W2017682357 hasConcept C184235292 @default.
• W2017682357 hasConcept C190283241 @default.
• W2017682357 hasConcept C2776235491 @default.
• W2017682357 hasConcept C2777562237 @default.
• W2017682357 hasConcept C502942594 @default.
• W2017682357 hasConcept C51551487 @default.
• W2017682357 hasConcept C55493867 @default.
• W2017682357 hasConcept C57074206 @default.
• W2017682357 hasConcept C62112901 @default.
• W2017682357 hasConcept C71924100 @default.
• W2017682357 hasConcept C86803240 @default.
• W2017682357 hasConcept C95444343 @default.
• W2017682357 hasConcept C97029542 @default.
• W2017682357 hasConceptScore W2017682357C121608353 @default.
• W2017682357 hasConceptScore W2017682357C126322002 @default.
• W2017682357 hasConceptScore W2017682357C132149769 @default.
• W2017682357 hasConceptScore W2017682357C142724271 @default.
• W2017682357 hasConceptScore W2017682357C16930146 @default.
• W2017682357 hasConceptScore W2017682357C184235292 @default.
• W2017682357 hasConceptScore W2017682357C190283241 @default.
• W2017682357 hasConceptScore W2017682357C2776235491 @default.
• W2017682357 hasConceptScore W2017682357C2777562237 @default.
• W2017682357 hasConceptScore W2017682357C502942594 @default.
• W2017682357 hasConceptScore W2017682357C51551487 @default.
• W2017682357 hasConceptScore W2017682357C55493867 @default.
• W2017682357 hasConceptScore W2017682357C57074206 @default.
• W2017682357 hasConceptScore W2017682357C62112901 @default.
• W2017682357 hasConceptScore W2017682357C71924100 @default.
• W2017682357 hasConceptScore W2017682357C86803240 @default.
• W2017682357 hasConceptScore W2017682357C95444343 @default.
• W2017682357 hasConceptScore W2017682357C97029542 @default.
• W2017682357 hasIssue "3" @default.

• next