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- W2017688807 abstract "A series of 2/3/4-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)amino]benzenesulfonamides, obtained from substituted isatins and 2-, 3- or 4-aminobenzenesulfonamide, showed low nanomolar inhibitory activity against the tumor associated carbonic anhydrase (CA, EC 4.2.1.1) isoforms IX and XII - recently validated antitumor drug targets, being much less effective as inhibitors of the off-target cytosolic isoforms CA I and II." @default.
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- W2017688807 date "2015-01-01" @default.
- W2017688807 modified "2023-10-16" @default.
- W2017688807 title "Discovery of novel isatin-based sulfonamides with potent and selective inhibition of the tumor-associated carbonic anhydrase isoforms IX and XII" @default.
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- W2017688807 doi "https://doi.org/10.1039/c5ob00688k" @default.
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