FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017689825> ?p ?o ?g. }

• W2017689825 endingPage "531" @default.
• W2017689825 startingPage "525" @default.
• W2017689825 abstract "Background & AimsThe long-term prognosis of peptic ulcers associated with neither Helicobacter pylori nor nonsteroidal anti-inflammatory drugs (NSAIDs) is unknown.MethodsThis 7-year prospective cohort study recruited patients with bleeding ulcers from January to December 2000. H pylori–negative idiopathic bleeding ulcers were defined as having tested negative for H pylori, having no exposure to aspirin or analgesics within 4 weeks before endoscopy, and having no other identifiable causative factors. After ulcers healed, patients were divided into 2 groups: patients with prior H pylori–negative idiopathic bleeding ulcers (H pylori–negative idiopathic ulcer cohort; n = 120) and those with H pylori–positive, NSAID-negative bleeding ulcers who received eradication therapy (H pylori ulcer cohort; n = 213). Both groups were followed for ≤7 years without gastroprotective therapy. The primary endpoints were recurrent ulcer bleeding and mortality.ResultsThe 7-year cumulative incidence of recurrent ulcer bleeding was 42.3% (95% CI, 36.5%–48.1%) in the H pylori–negative idiopathic ulcer cohort and 11.2% (95% CI, 8.8%–13.6%) in the H pylori ulcer cohort (a difference of 31.1%; 95% CI, 27.7%–34.5%; P < .0001). Significantly more patients died in the H pylori–negative idiopathic ulcer cohort (87.6%; 95% CI, 83.0%–92.2%) than in the H pylori ulcer cohort (37.3%; 95% CI, 34.0%–40.6%) with a difference of 50.3% (95% CI, 49.0%–51.6%; P < .0001).ConclusionsPatients with history of H pylori–negative idiopathic bleeding ulcers have a high risk of recurrent ulcer bleeding and mortality. The long-term prognosis of peptic ulcers associated with neither Helicobacter pylori nor nonsteroidal anti-inflammatory drugs (NSAIDs) is unknown. This 7-year prospective cohort study recruited patients with bleeding ulcers from January to December 2000. H pylori–negative idiopathic bleeding ulcers were defined as having tested negative for H pylori, having no exposure to aspirin or analgesics within 4 weeks before endoscopy, and having no other identifiable causative factors. After ulcers healed, patients were divided into 2 groups: patients with prior H pylori–negative idiopathic bleeding ulcers (H pylori–negative idiopathic ulcer cohort; n = 120) and those with H pylori–positive, NSAID-negative bleeding ulcers who received eradication therapy (H pylori ulcer cohort; n = 213). Both groups were followed for ≤7 years without gastroprotective therapy. The primary endpoints were recurrent ulcer bleeding and mortality. The 7-year cumulative incidence of recurrent ulcer bleeding was 42.3% (95% CI, 36.5%–48.1%) in the H pylori–negative idiopathic ulcer cohort and 11.2% (95% CI, 8.8%–13.6%) in the H pylori ulcer cohort (a difference of 31.1%; 95% CI, 27.7%–34.5%; P < .0001). Significantly more patients died in the H pylori–negative idiopathic ulcer cohort (87.6%; 95% CI, 83.0%–92.2%) than in the H pylori ulcer cohort (37.3%; 95% CI, 34.0%–40.6%) with a difference of 50.3% (95% CI, 49.0%–51.6%; P < .0001). Patients with history of H pylori–negative idiopathic bleeding ulcers have a high risk of recurrent ulcer bleeding and mortality." @default.
• W2017689825 created "2016-06-24" @default.
• W2017689825 creator A5000503303 @default.
• W2017689825 creator A5009718905 @default.
• W2017689825 creator A5011835164 @default.
• W2017689825 creator A5014087537 @default.
• W2017689825 creator A5035611017 @default.
• W2017689825 creator A5046528197 @default.
• W2017689825 creator A5047051372 @default.
• W2017689825 creator A5049274840 @default.
• W2017689825 creator A5052945397 @default.
• W2017689825 creator A5064937670 @default.
• W2017689825 creator A5067798951 @default.
• W2017689825 creator A5068228562 @default.
• W2017689825 creator A5071689583 @default.
• W2017689825 creator A5074050712 @default.
• W2017689825 creator A5087968813 @default.
• W2017689825 creator A5088639791 @default.
• W2017689825 date "2009-08-01" @default.
• W2017689825 modified "2023-10-18" @default.
• W2017689825 title "High Incidence of Mortality and Recurrent Bleeding in Patients With Helicobacter pylori–Negative Idiopathic Bleeding Ulcers" @default.
• W2017689825 cites W1972118686 @default.
• W2017689825 cites W1986868448 @default.
• W2017689825 cites W2004996738 @default.
• W2017689825 cites W2020001851 @default.
• W2017689825 cites W2057736131 @default.
• W2017689825 cites W2072593710 @default.
• W2017689825 cites W2079522249 @default.
• W2017689825 cites W2086394884 @default.
• W2017689825 cites W2108749138 @default.
• W2017689825 cites W2150914406 @default.
• W2017689825 cites W2322301603 @default.
• W2017689825 cites W2330799737 @default.
• W2017689825 cites W4246596951 @default.
• W2017689825 doi "https://doi.org/10.1053/j.gastro.2009.05.006" @default.
• W2017689825 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19445937" @default.
• W2017689825 hasPublicationYear "2009" @default.
• W2017689825 type Work @default.
• W2017689825 sameAs 2017689825 @default.
• W2017689825 citedByCount "120" @default.
• W2017689825 countsByYear W20176898252012 @default.
• W2017689825 countsByYear W20176898252013 @default.
• W2017689825 countsByYear W20176898252014 @default.
• W2017689825 countsByYear W20176898252015 @default.
• W2017689825 countsByYear W20176898252016 @default.
• W2017689825 countsByYear W20176898252017 @default.
• W2017689825 countsByYear W20176898252018 @default.
• W2017689825 countsByYear W20176898252019 @default.
• W2017689825 countsByYear W20176898252020 @default.
• W2017689825 countsByYear W20176898252021 @default.
• W2017689825 countsByYear W20176898252022 @default.
• W2017689825 countsByYear W20176898252023 @default.
• W2017689825 crossrefType "journal-article" @default.
• W2017689825 hasAuthorship W2017689825A5000503303 @default.
• W2017689825 hasAuthorship W2017689825A5009718905 @default.
• W2017689825 hasAuthorship W2017689825A5011835164 @default.
• W2017689825 hasAuthorship W2017689825A5014087537 @default.
• W2017689825 hasAuthorship W2017689825A5035611017 @default.
• W2017689825 hasAuthorship W2017689825A5046528197 @default.
• W2017689825 hasAuthorship W2017689825A5047051372 @default.
• W2017689825 hasAuthorship W2017689825A5049274840 @default.
• W2017689825 hasAuthorship W2017689825A5052945397 @default.
• W2017689825 hasAuthorship W2017689825A5064937670 @default.
• W2017689825 hasAuthorship W2017689825A5067798951 @default.
• W2017689825 hasAuthorship W2017689825A5068228562 @default.
• W2017689825 hasAuthorship W2017689825A5071689583 @default.
• W2017689825 hasAuthorship W2017689825A5074050712 @default.
• W2017689825 hasAuthorship W2017689825A5087968813 @default.
• W2017689825 hasAuthorship W2017689825A5088639791 @default.
• W2017689825 hasBestOaLocation W20176898251 @default.
• W2017689825 hasConcept C120665830 @default.
• W2017689825 hasConcept C121332964 @default.
• W2017689825 hasConcept C126322002 @default.
• W2017689825 hasConcept C141071460 @default.
• W2017689825 hasConcept C188816634 @default.
• W2017689825 hasConcept C201903717 @default.
• W2017689825 hasConcept C2776409635 @default.
• W2017689825 hasConcept C2777628954 @default.
• W2017689825 hasConcept C61511704 @default.
• W2017689825 hasConcept C71924100 @default.
• W2017689825 hasConcept C72563966 @default.
• W2017689825 hasConcept C88879693 @default.
• W2017689825 hasConcept C90924648 @default.
• W2017689825 hasConceptScore W2017689825C120665830 @default.
• W2017689825 hasConceptScore W2017689825C121332964 @default.
• W2017689825 hasConceptScore W2017689825C126322002 @default.
• W2017689825 hasConceptScore W2017689825C141071460 @default.
• W2017689825 hasConceptScore W2017689825C188816634 @default.
• W2017689825 hasConceptScore W2017689825C201903717 @default.
• W2017689825 hasConceptScore W2017689825C2776409635 @default.
• W2017689825 hasConceptScore W2017689825C2777628954 @default.
• W2017689825 hasConceptScore W2017689825C61511704 @default.
• W2017689825 hasConceptScore W2017689825C71924100 @default.
• W2017689825 hasConceptScore W2017689825C72563966 @default.
• W2017689825 hasConceptScore W2017689825C88879693 @default.
• W2017689825 hasConceptScore W2017689825C90924648 @default.
• W2017689825 hasIssue "2" @default.
• W2017689825 hasLocation W20176898251 @default.

• next