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• W2017691873 abstract "Apomorphine (Apo), a D1D2 Dopamine (DA) agonist, at high doses (500 μg/kg) induces a short-lasting insomnia, antagonized by a secondary injection of corticotropin-like intermediate lobe peptide (CLIP, 10 ng); these effects are also observed with hypophysectomized (hypoX) rats. The administration of the serotonin (5-HT) agonist 8-hydroxy-2-di-n-propylamino-tetralin (8-OHDPAT, 0.3 mg/kg) induces also an insomnia which, unlike Apo, is followed by a significant PS rebound. CLIP, again, antagonizes the 8-OHDPAT-induced insomnia. Finally, Bromocriptine (5 mg/kg), an agonist for both DA and 5-HT, induces first an insomnia (antagonized by CLIP), followed by a PS rebound; these effects persist in hypoX rats." @default.
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• W2017691873 date "1990-02-01" @default.
• W2017691873 modified "2023-10-07" @default.
• W2017691873 title "Proopiomelanocortin (POMC)-derived peptides and sleep in the rat Part 2 — Aminergic regulatory processes" @default.
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• W2017691873 doi "https://doi.org/10.1016/0143-4179(90)90043-x" @default.
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