Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017702963> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2017702963 endingPage "576" @default.
- W2017702963 startingPage "572" @default.
- W2017702963 abstract "Thyroid-stimulating immunoglobulin (TSI) activity was measured by radioreceptor assay in sera from patients with Graves' disease, Hashimoto's thyroiditis, and thyroid cancer. In untreated Graves' disease (47 cases), TSI index was significantly lower [76.7 +/- 1.4 (SE)] than the average of a normal control group (30 cases; 94.4 +/- 1.9). In untreated Hashimoto's thyroiditis (25 cases), it was also significantly lower (83.0 +/- 2.4). In patients with thyroid cancer (19 cases), there was no significant difference from normal controls. After 131I treatment, the TSI index in Graves' disease decreased during 2--4 months, then increased and reached normal levels in 1 yr. During propylthiouracil treatment, the TSI index increased and reached a normal level in 5--6 months without the decreasing phase seen after 131I treatment. Free T4 index values were gradually decreased by both treatments. There was no significant relationship between TSI index and thyroid antibodies (microsomal antibodies and thyroglobulin antibodies) in untreated Graves' disease or Hashimoto's thyroiditis. It is concluded that 1) in the sera of patients with Graves' disease and Hashimoto's thyroiditis, there are immunoglobulin Gs that can displace TSH binding to thyroid membranes; 2) these immunoglobulins Gs are different from the classic antithyroid antibodies; and 3) 131T treatment of Graves' disease may enhance TSI production during the first 1--2 months after therapy." @default.
- W2017702963 created "2016-06-24" @default.
- W2017702963 creator A5017939037 @default.
- W2017702963 creator A5035748305 @default.
- W2017702963 creator A5069500337 @default.
- W2017702963 creator A5082495160 @default.
- W2017702963 date "1979-04-01" @default.
- W2017702963 modified "2023-09-23" @default.
- W2017702963 title "Changes in Thyroid-Stimulating Immunoglobulins during Antithyroid Therapy*" @default.
- W2017702963 cites W1775749144 @default.
- W2017702963 cites W1964281708 @default.
- W2017702963 cites W1973011068 @default.
- W2017702963 cites W1994361909 @default.
- W2017702963 cites W2012377247 @default.
- W2017702963 cites W2021756202 @default.
- W2017702963 cites W2032404574 @default.
- W2017702963 cites W2082424837 @default.
- W2017702963 cites W2083568685 @default.
- W2017702963 cites W2087345409 @default.
- W2017702963 cites W2088247807 @default.
- W2017702963 cites W2142972511 @default.
- W2017702963 doi "https://doi.org/10.1210/jcem-48-4-572" @default.
- W2017702963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/581875" @default.
- W2017702963 hasPublicationYear "1979" @default.
- W2017702963 type Work @default.
- W2017702963 sameAs 2017702963 @default.
- W2017702963 citedByCount "135" @default.
- W2017702963 countsByYear W20177029632012 @default.
- W2017702963 countsByYear W20177029632015 @default.
- W2017702963 countsByYear W20177029632016 @default.
- W2017702963 countsByYear W20177029632018 @default.
- W2017702963 countsByYear W20177029632020 @default.
- W2017702963 countsByYear W20177029632021 @default.
- W2017702963 crossrefType "journal-article" @default.
- W2017702963 hasAuthorship W2017702963A5017939037 @default.
- W2017702963 hasAuthorship W2017702963A5035748305 @default.
- W2017702963 hasAuthorship W2017702963A5069500337 @default.
- W2017702963 hasAuthorship W2017702963A5082495160 @default.
- W2017702963 hasConcept C126322002 @default.
- W2017702963 hasConcept C134018914 @default.
- W2017702963 hasConcept C159654299 @default.
- W2017702963 hasConcept C163764329 @default.
- W2017702963 hasConcept C203014093 @default.
- W2017702963 hasConcept C2775960720 @default.
- W2017702963 hasConcept C2776652619 @default.
- W2017702963 hasConcept C2778696486 @default.
- W2017702963 hasConcept C2778835679 @default.
- W2017702963 hasConcept C50181227 @default.
- W2017702963 hasConcept C526584372 @default.
- W2017702963 hasConcept C71924100 @default.
- W2017702963 hasConceptScore W2017702963C126322002 @default.
- W2017702963 hasConceptScore W2017702963C134018914 @default.
- W2017702963 hasConceptScore W2017702963C159654299 @default.
- W2017702963 hasConceptScore W2017702963C163764329 @default.
- W2017702963 hasConceptScore W2017702963C203014093 @default.
- W2017702963 hasConceptScore W2017702963C2775960720 @default.
- W2017702963 hasConceptScore W2017702963C2776652619 @default.
- W2017702963 hasConceptScore W2017702963C2778696486 @default.
- W2017702963 hasConceptScore W2017702963C2778835679 @default.
- W2017702963 hasConceptScore W2017702963C50181227 @default.
- W2017702963 hasConceptScore W2017702963C526584372 @default.
- W2017702963 hasConceptScore W2017702963C71924100 @default.
- W2017702963 hasIssue "4" @default.
- W2017702963 hasLocation W20177029631 @default.
- W2017702963 hasLocation W20177029632 @default.
- W2017702963 hasOpenAccess W2017702963 @default.
- W2017702963 hasPrimaryLocation W20177029631 @default.
- W2017702963 hasRelatedWork W125470952 @default.
- W2017702963 hasRelatedWork W161873529 @default.
- W2017702963 hasRelatedWork W1966337757 @default.
- W2017702963 hasRelatedWork W2017702963 @default.
- W2017702963 hasRelatedWork W2074577918 @default.
- W2017702963 hasRelatedWork W2418570547 @default.
- W2017702963 hasRelatedWork W2422296866 @default.
- W2017702963 hasRelatedWork W2811327043 @default.
- W2017702963 hasRelatedWork W2890456764 @default.
- W2017702963 hasRelatedWork W72427302 @default.
- W2017702963 hasVolume "48" @default.
- W2017702963 isParatext "false" @default.
- W2017702963 isRetracted "false" @default.
- W2017702963 magId "2017702963" @default.
- W2017702963 workType "article" @default.