Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017705757> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2017705757 endingPage "29" @default.
- W2017705757 startingPage "25" @default.
- W2017705757 abstract "L'acide (méthyl-3 butyl)-5 propyl-5 barbiturique pouvait a prioriêtre oxydé, au niveau hépatique, sur la chaîne isoamyle ou la chaîne propyle. Des modèles de métabolites ont été préparés et le barbiturique a été administré au Chien et au Rat. L'obtention dans les urines d'un seul dérivé γ-hydroxylé confirme la facilité d'hydroxylation de la chaîne ramifiée et établit que le substituant propyle est moins sensible à l'oxydation que le groupe éthyle de l'amobarbital. 5-(3-Methylbutyl) 5-propyl barbituric acid could a priori undergo hepatic oxidation on either isoamyl or propyl side chains. Models of metabolites were synthesized and the barbiturate was administered to dogs and rats. Only a γ-hydroxy derivative was recovered in urine. This observation confirms the easy hydroxylation of the tertiary carbon in the 3-methyl-butyl group and establishes that the propyl side chain is less sensitive to oxidation than the ethyl side chain of amobarbital." @default.
- W2017705757 created "2016-06-24" @default.
- W2017705757 creator A5049607911 @default.
- W2017705757 creator A5068491943 @default.
- W2017705757 creator A5069610484 @default.
- W2017705757 creator A5079310857 @default.
- W2017705757 creator A5090589035 @default.
- W2017705757 date "1988-01-01" @default.
- W2017705757 modified "2023-09-25" @default.
- W2017705757 title "Compétition entre des chaînes propyle et isoamyle, vis à vis de l'hydroxylation hépatique, en série barbiturique" @default.
- W2017705757 cites W157754947 @default.
- W2017705757 cites W2004457064 @default.
- W2017705757 cites W2028088862 @default.
- W2017705757 cites W2031237950 @default.
- W2017705757 cites W2034820774 @default.
- W2017705757 cites W2043212697 @default.
- W2017705757 cites W2066100159 @default.
- W2017705757 cites W2066264664 @default.
- W2017705757 cites W2067468321 @default.
- W2017705757 cites W2088113801 @default.
- W2017705757 cites W2092340615 @default.
- W2017705757 cites W2314858877 @default.
- W2017705757 cites W2328686194 @default.
- W2017705757 cites W2436975333 @default.
- W2017705757 cites W1999262653 @default.
- W2017705757 doi "https://doi.org/10.1016/0223-5234(88)90163-8" @default.
- W2017705757 hasPublicationYear "1988" @default.
- W2017705757 type Work @default.
- W2017705757 sameAs 2017705757 @default.
- W2017705757 citedByCount "4" @default.
- W2017705757 crossrefType "journal-article" @default.
- W2017705757 hasAuthorship W2017705757A5049607911 @default.
- W2017705757 hasAuthorship W2017705757A5068491943 @default.
- W2017705757 hasAuthorship W2017705757A5069610484 @default.
- W2017705757 hasAuthorship W2017705757A5079310857 @default.
- W2017705757 hasAuthorship W2017705757A5090589035 @default.
- W2017705757 hasConcept C155647269 @default.
- W2017705757 hasConcept C169760540 @default.
- W2017705757 hasConcept C178790620 @default.
- W2017705757 hasConcept C181199279 @default.
- W2017705757 hasConcept C185592680 @default.
- W2017705757 hasConcept C204921945 @default.
- W2017705757 hasConcept C2776918552 @default.
- W2017705757 hasConcept C2778186239 @default.
- W2017705757 hasConcept C2779793070 @default.
- W2017705757 hasConcept C2781109383 @default.
- W2017705757 hasConcept C521977710 @default.
- W2017705757 hasConcept C71240020 @default.
- W2017705757 hasConcept C86803240 @default.
- W2017705757 hasConceptScore W2017705757C155647269 @default.
- W2017705757 hasConceptScore W2017705757C169760540 @default.
- W2017705757 hasConceptScore W2017705757C178790620 @default.
- W2017705757 hasConceptScore W2017705757C181199279 @default.
- W2017705757 hasConceptScore W2017705757C185592680 @default.
- W2017705757 hasConceptScore W2017705757C204921945 @default.
- W2017705757 hasConceptScore W2017705757C2776918552 @default.
- W2017705757 hasConceptScore W2017705757C2778186239 @default.
- W2017705757 hasConceptScore W2017705757C2779793070 @default.
- W2017705757 hasConceptScore W2017705757C2781109383 @default.
- W2017705757 hasConceptScore W2017705757C521977710 @default.
- W2017705757 hasConceptScore W2017705757C71240020 @default.
- W2017705757 hasConceptScore W2017705757C86803240 @default.
- W2017705757 hasIssue "1" @default.
- W2017705757 hasLocation W20177057571 @default.
- W2017705757 hasOpenAccess W2017705757 @default.
- W2017705757 hasPrimaryLocation W20177057571 @default.
- W2017705757 hasRelatedWork W1543947429 @default.
- W2017705757 hasRelatedWork W1975278455 @default.
- W2017705757 hasRelatedWork W1994764501 @default.
- W2017705757 hasRelatedWork W1999256202 @default.
- W2017705757 hasRelatedWork W2017705757 @default.
- W2017705757 hasRelatedWork W2043212697 @default.
- W2017705757 hasRelatedWork W2061616338 @default.
- W2017705757 hasRelatedWork W2088043606 @default.
- W2017705757 hasRelatedWork W2227030711 @default.
- W2017705757 hasRelatedWork W2065255062 @default.
- W2017705757 hasVolume "23" @default.
- W2017705757 isParatext "false" @default.
- W2017705757 isRetracted "false" @default.
- W2017705757 magId "2017705757" @default.
- W2017705757 workType "article" @default.