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- W2017755819 endingPage "677" @default.
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- W2017755819 abstract "Morphological complexity of neurons contributes to their functional complexity. How neurons generate different dendritic patterns is not known. We identified the sequoia mutant from a previous screen for dendrite mutants. Here we report that Sequoia is a pan-neural nuclear protein containing two putative zinc fingers homologous to the DNA binding domain of Tramtrack. sequoia mutants affect the cell fate decision of a small subset of neurons but have global effects on axon and dendrite morphologies of most and possibly all neurons. In support of sequoia as a specific regulator of neuronal morphogenesis, microarray experiments indicate that sequoia may regulate downstream genes that are important for executing neurite development rather than altering a variety of molecules that specify cell fates." @default.
- W2017755819 created "2016-06-24" @default.
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- W2017755819 date "2001-11-01" @default.
- W2017755819 modified "2023-10-17" @default.
- W2017755819 title "Sequoia, a Tramtrack-Related Zinc Finger Protein, Functions as a Pan-Neural Regulator for Dendrite and Axon Morphogenesis in Drosophila" @default.
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- W2017755819 doi "https://doi.org/10.1016/s1534-5807(01)00072-7" @default.
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