FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017756927> ?p ?o ?g. }

• W2017756927 endingPage "372" @default.
• W2017756927 startingPage "368" @default.
• W2017756927 abstract "Aquaporin-4 (AQP4) is a water channel expressed in astrocyte end-feet lining the blood–brain barrier. AQP4 deletion in mice is associated with improved outcomes in global cerebral ischemia produced by transient carotid artery occlusion, and focal cerebral ischemia produced by permanent middle cerebral artery occlusion (MCAO). Here, we investigated the consequences of 1-h transient MCAO produced by intraluminal suture blockade followed by 23 h of reperfusion. In nine AQP4+/+ and nine AQP4−/− mice, infarct volume was significantly reduced by an average of 39 ± 4% at 24 h in AQP4−/− mice, cerebral hemispheric edema was reduced by 23 ± 3%, and Evans Blue extravasation was reduced by 31 ± 2% (mean ± SEM). Diffusion-weighted magnetic resonance imaging showed greatest reduction in apparent diffusion coefficient around the occlusion site after reperfusion, with remarkably lesser reduction in AQP4−/− mice. The reduced infarct volume in AQP4−/− mice following transient MCAO supports the potential utility of therapeutic AQP4 inhibition in stroke." @default.
• W2017756927 created "2016-06-24" @default.
• W2017756927 creator A5036633860 @default.
• W2017756927 creator A5040370380 @default.
• W2017756927 creator A5042356327 @default.
• W2017756927 creator A5076261073 @default.
• W2017756927 date "2015-01-01" @default.
• W2017756927 modified "2023-10-14" @default.
• W2017756927 title "Reduced brain edema and infarct volume in aquaporin-4 deficient mice after transient focal cerebral ischemia" @default.
• W2017756927 cites W1495656315 @default.
• W2017756927 cites W1535419310 @default.
• W2017756927 cites W1578750681 @default.
• W2017756927 cites W1963766511 @default.
• W2017756927 cites W1974587361 @default.
• W2017756927 cites W1977225498 @default.
• W2017756927 cites W1980829307 @default.
• W2017756927 cites W1982084400 @default.
• W2017756927 cites W1988086690 @default.
• W2017756927 cites W1989915815 @default.
• W2017756927 cites W1990711311 @default.
• W2017756927 cites W1993258467 @default.
• W2017756927 cites W1995785702 @default.
• W2017756927 cites W2011991034 @default.
• W2017756927 cites W2031145279 @default.
• W2017756927 cites W2040733706 @default.
• W2017756927 cites W2041380818 @default.
• W2017756927 cites W2046611979 @default.
• W2017756927 cites W2057509573 @default.
• W2017756927 cites W2060701169 @default.
• W2017756927 cites W2063541896 @default.
• W2017756927 cites W2065525398 @default.
• W2017756927 cites W2086060734 @default.
• W2017756927 cites W2091722185 @default.
• W2017756927 cites W2092953724 @default.
• W2017756927 cites W2105443363 @default.
• W2017756927 cites W2119390004 @default.
• W2017756927 cites W2119734225 @default.
• W2017756927 cites W2124292468 @default.
• W2017756927 cites W2137232579 @default.
• W2017756927 cites W2139597377 @default.
• W2017756927 cites W2169079203 @default.
• W2017756927 doi "https://doi.org/10.1016/j.neulet.2014.10.040" @default.
• W2017756927 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4737527" @default.
• W2017756927 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25449874" @default.
• W2017756927 hasPublicationYear "2015" @default.
• W2017756927 type Work @default.
• W2017756927 sameAs 2017756927 @default.
• W2017756927 citedByCount "97" @default.
• W2017756927 countsByYear W20177569272015 @default.
• W2017756927 countsByYear W20177569272016 @default.
• W2017756927 countsByYear W20177569272017 @default.
• W2017756927 countsByYear W20177569272018 @default.
• W2017756927 countsByYear W20177569272019 @default.
• W2017756927 countsByYear W20177569272020 @default.
• W2017756927 countsByYear W20177569272021 @default.
• W2017756927 countsByYear W20177569272022 @default.
• W2017756927 countsByYear W20177569272023 @default.
• W2017756927 crossrefType "journal-article" @default.
• W2017756927 hasAuthorship W2017756927A5036633860 @default.
• W2017756927 hasAuthorship W2017756927A5040370380 @default.
• W2017756927 hasAuthorship W2017756927A5042356327 @default.
• W2017756927 hasAuthorship W2017756927A5076261073 @default.
• W2017756927 hasBestOaLocation W20177569272 @default.
• W2017756927 hasConcept C126322002 @default.
• W2017756927 hasConcept C126838900 @default.
• W2017756927 hasConcept C127413603 @default.
• W2017756927 hasConcept C142724271 @default.
• W2017756927 hasConcept C143409427 @default.
• W2017756927 hasConcept C15755913 @default.
• W2017756927 hasConcept C2776268601 @default.
• W2017756927 hasConcept C2777542381 @default.
• W2017756927 hasConcept C2777649898 @default.
• W2017756927 hasConcept C2779493303 @default.
• W2017756927 hasConcept C2779540182 @default.
• W2017756927 hasConcept C2780645631 @default.
• W2017756927 hasConcept C2780886150 @default.
• W2017756927 hasConcept C42219234 @default.
• W2017756927 hasConcept C529278444 @default.
• W2017756927 hasConcept C541997718 @default.
• W2017756927 hasConcept C70816921 @default.
• W2017756927 hasConcept C71924100 @default.
• W2017756927 hasConcept C78519656 @default.
• W2017756927 hasConceptScore W2017756927C126322002 @default.
• W2017756927 hasConceptScore W2017756927C126838900 @default.
• W2017756927 hasConceptScore W2017756927C127413603 @default.
• W2017756927 hasConceptScore W2017756927C142724271 @default.
• W2017756927 hasConceptScore W2017756927C143409427 @default.
• W2017756927 hasConceptScore W2017756927C15755913 @default.
• W2017756927 hasConceptScore W2017756927C2776268601 @default.
• W2017756927 hasConceptScore W2017756927C2777542381 @default.
• W2017756927 hasConceptScore W2017756927C2777649898 @default.
• W2017756927 hasConceptScore W2017756927C2779493303 @default.
• W2017756927 hasConceptScore W2017756927C2779540182 @default.
• W2017756927 hasConceptScore W2017756927C2780645631 @default.
• W2017756927 hasConceptScore W2017756927C2780886150 @default.
• W2017756927 hasConceptScore W2017756927C42219234 @default.
• W2017756927 hasConceptScore W2017756927C529278444 @default.
• W2017756927 hasConceptScore W2017756927C541997718 @default.

• next