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• W2017758384 endingPage "1100" @default.
• W2017758384 startingPage "1054" @default.
• W2017758384 abstract "The components of life must survive in a cell long enough to perform their function in that cell. Because the rate of attack by water increases with temperature, we can, in principle, predict a maximum temperature above which an active terrestrial metabolism cannot function by analysis of the decomposition rates of the components of life, and comparison of those rates with the metabolites’ minimum metabolic half-lives. The present study is a first step in this direction, providing an analytical framework and method, and analyzing the stability of 63 small molecule metabolites based on literature data. Assuming that attack by water follows a first order rate equation, we extracted decomposition rate constants from literature data and estimated their statistical reliability. The resulting rate equations were then used to give a measure of confidence in the half-life of the metabolite concerned at different temperatures. There is little reliable data on metabolite decomposition or hydrolysis rates in the literature, the data is mostly confined to a small number of classes of chemicals, and the data available are sometimes mutually contradictory because of varying reaction conditions. However, a preliminary analysis suggests that terrestrial biochemistry is limited to environments below ~150–180 °C. We comment briefly on why pressure is likely to have a small effect on this." @default.
• W2017758384 created "2016-06-24" @default.
• W2017758384 creator A5004962359 @default.
• W2017758384 creator A5022344002 @default.
• W2017758384 creator A5083801513 @default.
• W2017758384 date "2015-03-26" @default.
• W2017758384 modified "2023-09-26" @default.
• W2017758384 title "Prediction of the Maximum Temperature for Life Based on the Stability of Metabolites to Decomposition in Water" @default.
• W2017758384 cites W1513720422 @default.
• W2017758384 cites W1527027330 @default.
• W2017758384 cites W1587070645 @default.
• W2017758384 cites W1604750962 @default.
• W2017758384 cites W1633704547 @default.
• W2017758384 cites W1747057328 @default.
• W2017758384 cites W1778882962 @default.
• W2017758384 cites W1830114392 @default.
• W2017758384 cites W1925866711 @default.
• W2017758384 cites W1944789189 @default.
• W2017758384 cites W1964205591 @default.
• W2017758384 cites W1966067528 @default.
• W2017758384 cites W1967482719 @default.
• W2017758384 cites W1967924059 @default.
• W2017758384 cites W1968047155 @default.
• W2017758384 cites W1968803553 @default.
• W2017758384 cites W1971496446 @default.
• W2017758384 cites W1972607828 @default.
• W2017758384 cites W1977772490 @default.
• W2017758384 cites W1979514665 @default.
• W2017758384 cites W1980003022 @default.
• W2017758384 cites W1982033514 @default.
• W2017758384 cites W1982053506 @default.
• W2017758384 cites W1982070685 @default.
• W2017758384 cites W1983384197 @default.
• W2017758384 cites W1986192969 @default.
• W2017758384 cites W1987946824 @default.
• W2017758384 cites W1988950044 @default.
• W2017758384 cites W1989095938 @default.
• W2017758384 cites W1991196512 @default.
• W2017758384 cites W1992822591 @default.
• W2017758384 cites W1993656875 @default.
• W2017758384 cites W1995701679 @default.
• W2017758384 cites W1998281556 @default.
• W2017758384 cites W2000583796 @default.
• W2017758384 cites W2000668556 @default.
• W2017758384 cites W2001152986 @default.
• W2017758384 cites W2001237138 @default.
• W2017758384 cites W2003949804 @default.
• W2017758384 cites W2004678782 @default.
• W2017758384 cites W2008362578 @default.
• W2017758384 cites W2009130998 @default.
• W2017758384 cites W2009689313 @default.
• W2017758384 cites W2009758786 @default.
• W2017758384 cites W2013514646 @default.
• W2017758384 cites W2015299166 @default.
• W2017758384 cites W2016055668 @default.
• W2017758384 cites W2016347501 @default.
• W2017758384 cites W2019252943 @default.
• W2017758384 cites W2020686153 @default.
• W2017758384 cites W2021039308 @default.
• W2017758384 cites W2023551301 @default.
• W2017758384 cites W2024227583 @default.
• W2017758384 cites W2024321928 @default.
• W2017758384 cites W2025717115 @default.
• W2017758384 cites W2026145627 @default.
• W2017758384 cites W2029175543 @default.
• W2017758384 cites W2029609157 @default.
• W2017758384 cites W2029864727 @default.
• W2017758384 cites W2031497157 @default.
• W2017758384 cites W2033852303 @default.
• W2017758384 cites W2035514228 @default.
• W2017758384 cites W2035938536 @default.
• W2017758384 cites W2035972791 @default.
• W2017758384 cites W2038599593 @default.
• W2017758384 cites W2043638286 @default.
• W2017758384 cites W2044435357 @default.
• W2017758384 cites W2045428054 @default.
• W2017758384 cites W2046297419 @default.
• W2017758384 cites W2047044987 @default.
• W2017758384 cites W2048478510 @default.
• W2017758384 cites W2050046369 @default.
• W2017758384 cites W2050439268 @default.
• W2017758384 cites W2052271795 @default.
• W2017758384 cites W2053947688 @default.
• W2017758384 cites W2054132780 @default.
• W2017758384 cites W2057003930 @default.
• W2017758384 cites W2058499035 @default.
• W2017758384 cites W2060746784 @default.
• W2017758384 cites W2060975426 @default.
• W2017758384 cites W2063099733 @default.
• W2017758384 cites W2063964894 @default.
• W2017758384 cites W2065071332 @default.
• W2017758384 cites W2066620275 @default.
• W2017758384 cites W2068046099 @default.
• W2017758384 cites W2068519253 @default.
• W2017758384 cites W2068578053 @default.
• W2017758384 cites W2072366550 @default.
• W2017758384 cites W2073365346 @default.
• W2017758384 cites W2073776293 @default.

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