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- W2017762623 abstract "hough an estimated 1 million new cases oftuberculosis (TB) occur in children world-wide each year, pediatric TB has not beengiven the same priority as its adultcounterpart(1). Advances in diagnosis and treatmentare lagging behind – the major limitation inperforming treatment trials in children is the lack of adefinitive gold standard for diagnosis andmonitoring. As a result, regimens and dosages ofanti-TB drugs tested in adults are often extrapolatedto children. The efficacy of short-coursechemotherapy (SCC) regimens for the treatment ofpulmonary TB was first demonstrated in adults inthe1970s; this was followed by trials for extra-pulmonary and childhood TB. Even before SCCbecame the norm, the phenomenon of “lag phase” inmycobacteria exposed to anti-TB drugs" @default.
- W2017762623 created "2016-06-24" @default.
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- W2017762623 date "2010-01-01" @default.
- W2017762623 modified "2023-09-26" @default.
- W2017762623 title "Evidence-based treatment of tuberculosis for children: The unfinished agenda" @default.
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- W2017762623 doi "https://doi.org/10.1007/s13312-010-0003-8" @default.
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