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- W2017776577 abstract "In this study, 2,6-dimethyl-β-cyclodextrin (DM-β-CD) functionalized graphene nanosheets (DM-β-CD-GNs) were successfully synthesized by a simple wet-chemical strategy. The as obtained DM-β-CD-GNs were characterized by UV–vis spectroscopy, Fourier transform Infrared (FT-IR) spectroscopy, atomic force microscopy (AFM) and transmission electron microscopy (TEM). The new nanocomposite possesses the unique properties of graphene (large surface area and high conductivity) and DM-β-CD (high supramolecular recognition and enrichment capability). Based on the above properties, a highly sensitive electrochemical sensor was developed to detect two flavonoid drugs (isoquercitrin and baicalin). At the DM-β-CD-GNs modified glassy carbon electrode (DM-β-CD-GNs/GCE), the peak currents of the two drugs increased dramatically compared with that on the bare GCE and GNs/GCE which due to the synergetic effects of GNs and DM-β-CD molecules. The linear response ranges for isoquercitrin and baicalin are 10 nM–3.0 μM and 0.04 μM –3.0 μM, with the detection limits of 4 nM and 10 nM, respectively. The method might open up a new possibility for the widespread use of electrochemical sensors for monitoring of ultra-trace flavonoid drugs owing to its advantages of simple preparation, low cost, high sensitivity, good stability and reproducibility." @default.
- W2017776577 created "2016-06-24" @default.
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- W2017776577 date "2014-08-01" @default.
- W2017776577 modified "2023-10-06" @default.
- W2017776577 title "Electrochemical sensor for ultrasensitive determination of isoquercitrin and baicalin based on DM-β-cyclodextrin functionalized graphene nanosheets" @default.
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- W2017776577 doi "https://doi.org/10.1016/j.bios.2014.02.051" @default.
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