Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017781467> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2017781467 endingPage "263" @default.
- W2017781467 startingPage "258" @default.
- W2017781467 abstract "A crude organic solvent extract of Alangium cf. longiflorum exhibited potent inhibition of hypoxia-induced HIF-1 transcriptional activity in human U251 glioma cells. Dereplication and bioactivity-guided fractionation, including Sephadex LH-20 and chiral HPLC chromatographies, led to the isolation of tubulosine (1), 9-desmethyltubulosine (2), and isotubulosine (3). Structures were verified by complete 1H and 13C assignments using 1D- and 2D-NMR techniques. Tubulosine strongly inhibited HIF-1 transcriptional activity, isotubulosine was devoid of activity, and 9-desmethyltubulosine possessed 6-fold less potency than tubulosine." @default.
- W2017781467 created "2016-06-24" @default.
- W2017781467 creator A5000029047 @default.
- W2017781467 creator A5026711086 @default.
- W2017781467 creator A5041692512 @default.
- W2017781467 creator A5050766337 @default.
- W2017781467 creator A5054008918 @default.
- W2017781467 creator A5084816440 @default.
- W2017781467 creator A5090399618 @default.
- W2017781467 date "2008-02-01" @default.
- W2017781467 modified "2023-10-04" @default.
- W2017781467 title "Separation and SAR Study of HIF-1α Inhibitory Tubulosines from <i>Alangium cf. longiflorum</i>" @default.
- W2017781467 doi "https://doi.org/10.1055/s-2008-1034315" @default.
- W2017781467 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18302092" @default.
- W2017781467 hasPublicationYear "2008" @default.
- W2017781467 type Work @default.
- W2017781467 sameAs 2017781467 @default.
- W2017781467 citedByCount "15" @default.
- W2017781467 countsByYear W20177814672014 @default.
- W2017781467 countsByYear W20177814672015 @default.
- W2017781467 countsByYear W20177814672018 @default.
- W2017781467 countsByYear W20177814672019 @default.
- W2017781467 countsByYear W20177814672020 @default.
- W2017781467 countsByYear W20177814672021 @default.
- W2017781467 countsByYear W20177814672023 @default.
- W2017781467 crossrefType "journal-article" @default.
- W2017781467 hasAuthorship W2017781467A5000029047 @default.
- W2017781467 hasAuthorship W2017781467A5026711086 @default.
- W2017781467 hasAuthorship W2017781467A5041692512 @default.
- W2017781467 hasAuthorship W2017781467A5050766337 @default.
- W2017781467 hasAuthorship W2017781467A5054008918 @default.
- W2017781467 hasAuthorship W2017781467A5084816440 @default.
- W2017781467 hasAuthorship W2017781467A5090399618 @default.
- W2017781467 hasConcept C163994747 @default.
- W2017781467 hasConcept C178790620 @default.
- W2017781467 hasConcept C179998833 @default.
- W2017781467 hasConcept C181199279 @default.
- W2017781467 hasConcept C185592680 @default.
- W2017781467 hasConcept C43617362 @default.
- W2017781467 hasConcept C540031477 @default.
- W2017781467 hasConcept C55493867 @default.
- W2017781467 hasConcept C7836513 @default.
- W2017781467 hasConcept C86803240 @default.
- W2017781467 hasConcept C97428945 @default.
- W2017781467 hasConceptScore W2017781467C163994747 @default.
- W2017781467 hasConceptScore W2017781467C178790620 @default.
- W2017781467 hasConceptScore W2017781467C179998833 @default.
- W2017781467 hasConceptScore W2017781467C181199279 @default.
- W2017781467 hasConceptScore W2017781467C185592680 @default.
- W2017781467 hasConceptScore W2017781467C43617362 @default.
- W2017781467 hasConceptScore W2017781467C540031477 @default.
- W2017781467 hasConceptScore W2017781467C55493867 @default.
- W2017781467 hasConceptScore W2017781467C7836513 @default.
- W2017781467 hasConceptScore W2017781467C86803240 @default.
- W2017781467 hasConceptScore W2017781467C97428945 @default.
- W2017781467 hasIssue "3" @default.
- W2017781467 hasLocation W20177814671 @default.
- W2017781467 hasLocation W20177814672 @default.
- W2017781467 hasOpenAccess W2017781467 @default.
- W2017781467 hasPrimaryLocation W20177814671 @default.
- W2017781467 hasRelatedWork W1978740625 @default.
- W2017781467 hasRelatedWork W1987033538 @default.
- W2017781467 hasRelatedWork W1993572314 @default.
- W2017781467 hasRelatedWork W2022807649 @default.
- W2017781467 hasRelatedWork W2031618841 @default.
- W2017781467 hasRelatedWork W2417209194 @default.
- W2017781467 hasRelatedWork W2430129257 @default.
- W2017781467 hasRelatedWork W2491525353 @default.
- W2017781467 hasRelatedWork W258590310 @default.
- W2017781467 hasRelatedWork W2057906836 @default.
- W2017781467 hasVolume "74" @default.
- W2017781467 isParatext "false" @default.
- W2017781467 isRetracted "false" @default.
- W2017781467 magId "2017781467" @default.
- W2017781467 workType "article" @default.