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• W2017805968 abstract "To describe the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) at a university hospital during a 14-month period.Prospective laboratory-based surveillance for MRSA with descriptive epidemiology based on medical chart review and characterization of strains by DNA typing, using pulsed-field gel electrophoresis (PFGE).An 850-bed tertiary care university hospital.Patients with clinical isolates of MRSA.Determination whether MRSA isolates were community- or hospital-related.Among 87 patients with MRSA, 36 (41%) had community-acquired infections. Community acquisition was associated with recent hospitalization, previous antibiotic therapy, nursing home residence, and intravenous drug use. Greater than 3 months had elapsed from the time of discharge for 13 (62%) of the 21 patients with community-acquired isolates hospitalized within the last year. Eight patients (22%) with community-acquired MRSA had no discernible risk factors. PFGE allowed differentiation of 35 distinct whole-cell DNA patterns; heterogeneity was seen among both nosocomial and community-acquired isolates, with few instances of cross-transmission.Our data suggest an increase in community acquisition of MRSA. PFGE demonstrated heterogeneity of MRSA isolates from both the community and the hospital setting." @default.
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• W2017805968 date "1995-01-01" @default.
• W2017805968 modified "2023-10-18" @default.
• W2017805968 title "The Evolving Epidemiology of Methicillin-Resistant Staphylococcus aureus at a University Hospital" @default.
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• W2017805968 doi "https://doi.org/10.1086/646996" @default.
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