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• W2017809175 endingPage "1477" @default.
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• W2017809175 abstract "Cu(I)-catalyzed Azide-Alkyne Cycloaddition (CuAAC) is often utilized in medicinal chemistry to make the triazole moiety as it acts as a non-classical bioisostere of the peptide bond. This useful technique can also be applied in the fragment-based assembly of molecular libraries for high-throughput screening. This minireview outlines the application of click-chemistry in the synthesis of enzyme inhibitors with the triazole moiety. Keywords: Cycloaddition, drug discovery, enzymes, high-throughput screening, organic synthesis." @default.
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• W2017809175 date "2014-03-31" @default.
• W2017809175 modified "2023-09-25" @default.
• W2017809175 title "Use of Click-Chemistry in the Development of Peptidomimetic Enzyme Inhibitors" @default.
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• W2017809175 doi "https://doi.org/10.2174/0929867321666131218093611" @default.
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