FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017828611> ?p ?o ?g. }

• W2017828611 endingPage "314" @default.
• W2017828611 startingPage "307" @default.
• W2017828611 abstract "The biomechanical role of the vertebral cortical shell remains poorly understood. Using high-resolution finite element modeling of a cohort of elderly vertebrae, we found that the biomechanical role of the shell can be substantial and that the load sharing between the cortical and trabecular bone is complex. As a result, a more integrative measure of the trabecular and cortical bone should improve noninvasive assessment of fracture risk and treatments.A fundamental but poorly understood issue in the assessment of both osteoporotic vertebral fracture risk and effects of treatment is the role of the trabecular bone and cortical shell in the load-carrying capacity of the vertebral body.High-resolution microCT-based finite element models were developed for 13 elderly human vertebrae (age range: 54-87 years; 74.6 +/- 9.4 years), and parameter studies-with and without endplates-were performed to determine the role of the shell versus trabecular bone and the effect of model assumptions.Across vertebrae, whereas the average thickness of the cortical shell was only 0.38 +/- 0.06 mm, the shell mass fraction (shell mass/total bone mass)-not including the endplates-ranged from 0.21 to 0.39. The maximum load fraction taken by the shell varied from 0.38 to 0.54 across vertebrae and occurred at the narrowest section. The maximum load fraction taken by the trabecular bone varied from 0.76 to 0.89 across vertebrae and occurred near the endplates. Neither the maximum shell load fraction nor the maximum trabecular load fraction depended on any of the densitometric or morphologic properties of the vertebra, indicating the complex nature of the load sharing mechanism. The variation of the shell load-carrying capacity across vertebrae was significantly altered by the removal of endplates, although these models captured the overall trend within a vertebra.The biomechanical role of the thin cortical shell in the vertebral body can be substantial, being about 45% at the midtransverse section but as low as 15% close to the endplates. As a result of the complexity of load sharing, sampling of only midsection trabecular bone as a strength surrogate misses important biomechanical information. A more integrative approach that combines the structural role of both cortical and trabecular bone should improve noninvasive assessment of vertebral bone strength in vivo." @default.
• W2017828611 created "2016-06-24" @default.
• W2017828611 creator A5032386875 @default.
• W2017828611 creator A5036451828 @default.
• W2017828611 creator A5060491136 @default.
• W2017828611 creator A5084354004 @default.
• W2017828611 date "2006-02-01" @default.
• W2017828611 modified "2023-10-12" @default.
• W2017828611 title "Cortical and Trabecular Load Sharing in the Human Vertebral Body" @default.
• W2017828611 cites W1596269324 @default.
• W2017828611 cites W1972766017 @default.
• W2017828611 cites W1975184549 @default.
• W2017828611 cites W1976626695 @default.
• W2017828611 cites W1982467614 @default.
• W2017828611 cites W1987809980 @default.
• W2017828611 cites W1992498675 @default.
• W2017828611 cites W1992647292 @default.
• W2017828611 cites W2001854130 @default.
• W2017828611 cites W2007965763 @default.
• W2017828611 cites W2017565340 @default.
• W2017828611 cites W2023100986 @default.
• W2017828611 cites W2027670888 @default.
• W2017828611 cites W2029097920 @default.
• W2017828611 cites W2038111254 @default.
• W2017828611 cites W2038990885 @default.
• W2017828611 cites W2064979257 @default.
• W2017828611 cites W2068947159 @default.
• W2017828611 cites W2070559672 @default.
• W2017828611 cites W2071366384 @default.
• W2017828611 cites W2072572444 @default.
• W2017828611 cites W2076349714 @default.
• W2017828611 cites W2079396324 @default.
• W2017828611 cites W2092608305 @default.
• W2017828611 cites W2095150495 @default.
• W2017828611 cites W2102087333 @default.
• W2017828611 cites W2110828193 @default.
• W2017828611 cites W2113162921 @default.
• W2017828611 cites W2114276548 @default.
• W2017828611 cites W2117135793 @default.
• W2017828611 cites W2131504203 @default.
• W2017828611 cites W2133185517 @default.
• W2017828611 cites W2145069783 @default.
• W2017828611 cites W2149793650 @default.
• W2017828611 cites W2167665629 @default.
• W2017828611 cites W2317589070 @default.
• W2017828611 cites W2411746119 @default.
• W2017828611 cites W4248145551 @default.
• W2017828611 doi "https://doi.org/10.1359/jbmr.2006.21.2.307" @default.
• W2017828611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16418787" @default.
• W2017828611 hasPublicationYear "2006" @default.
• W2017828611 type Work @default.
• W2017828611 sameAs 2017828611 @default.
• W2017828611 citedByCount "247" @default.
• W2017828611 countsByYear W20178286112012 @default.
• W2017828611 countsByYear W20178286112013 @default.
• W2017828611 countsByYear W20178286112014 @default.
• W2017828611 countsByYear W20178286112015 @default.
• W2017828611 countsByYear W20178286112016 @default.
• W2017828611 countsByYear W20178286112017 @default.
• W2017828611 countsByYear W20178286112018 @default.
• W2017828611 countsByYear W20178286112019 @default.
• W2017828611 countsByYear W20178286112020 @default.
• W2017828611 countsByYear W20178286112021 @default.
• W2017828611 countsByYear W20178286112022 @default.
• W2017828611 countsByYear W20178286112023 @default.
• W2017828611 crossrefType "journal-article" @default.
• W2017828611 hasAuthorship W2017828611A5032386875 @default.
• W2017828611 hasAuthorship W2017828611A5036451828 @default.
• W2017828611 hasAuthorship W2017828611A5060491136 @default.
• W2017828611 hasAuthorship W2017828611A5084354004 @default.
• W2017828611 hasBestOaLocation W20178286111 @default.
• W2017828611 hasConcept C105702510 @default.
• W2017828611 hasConcept C120314980 @default.
• W2017828611 hasConcept C136229726 @default.
• W2017828611 hasConcept C142724271 @default.
• W2017828611 hasConcept C159985019 @default.
• W2017828611 hasConcept C170700871 @default.
• W2017828611 hasConcept C192562407 @default.
• W2017828611 hasConcept C2776541429 @default.
• W2017828611 hasConcept C2781052500 @default.
• W2017828611 hasConcept C2781451080 @default.
• W2017828611 hasConcept C3018268312 @default.
• W2017828611 hasConcept C3019828297 @default.
• W2017828611 hasConcept C41008148 @default.
• W2017828611 hasConcept C71924100 @default.
• W2017828611 hasConceptScore W2017828611C105702510 @default.
• W2017828611 hasConceptScore W2017828611C120314980 @default.
• W2017828611 hasConceptScore W2017828611C136229726 @default.
• W2017828611 hasConceptScore W2017828611C142724271 @default.
• W2017828611 hasConceptScore W2017828611C159985019 @default.
• W2017828611 hasConceptScore W2017828611C170700871 @default.
• W2017828611 hasConceptScore W2017828611C192562407 @default.
• W2017828611 hasConceptScore W2017828611C2776541429 @default.
• W2017828611 hasConceptScore W2017828611C2781052500 @default.
• W2017828611 hasConceptScore W2017828611C2781451080 @default.
• W2017828611 hasConceptScore W2017828611C3018268312 @default.
• W2017828611 hasConceptScore W2017828611C3019828297 @default.
• W2017828611 hasConceptScore W2017828611C41008148 @default.

• next