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- W2017860265 abstract "It has been almost 40 years since the discovery of the hepatitis B virus (HBV) and yet the disease it causes, hepatitis B, remains a major public health challenge. Despite the development of an effective vaccine and its implementation throughout the 1980s, there is still a huge burden of liver disease due to chronic hepatitis B (CHB). Worldwide, more than 400 million people have CHB; the majority are in the Asia-Pacific region, and there are at least one million deaths each year as a direct consequence of infection. The main public health strategy to control hepatitis B for the last 20 years has been primary prevention through vaccination, and excellent progress has been made. However, to reduce the complications of CHB, which include the development of cirrhosis with hepatic decompensation and hepatocellular carcinoma (HCC) for the at-risk population, an additional strategy is urgently required. The World Heath Organization (WHO) has termed this strategy chemoprevention, which is the use of antiviral agents to control HBV replication and thereby block the development of the complications that make HBV infection the ninth leading cause of death worldwide." @default.
- W2017860265 created "2016-06-24" @default.
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- W2017860265 date "2006-05-01" @default.
- W2017860265 modified "2023-09-26" @default.
- W2017860265 title "The Control of Chronic Hepatitis B: The Role for Chemoprevention" @default.
- W2017860265 doi "https://doi.org/10.1055/s-2006-939749" @default.
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