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- W2017860706 abstract "The Ellman group has been one of the most influential in the development and widespread adoption of combinatorial chemistry techniques for biomedical research. Their work has included substantial methodological development for library synthesis with a particular focus on new scaffolds rationally targeted to biomolecules of interest and biologically relevant natural products. Herein we analyze a representative set of libraries from this group with respect to their biological and biomedical relevance in comparison to existing drugs and probe compounds. This analysis reveals that the Ellman group has not only provided new methodologies to the community but also provided libraries with unique potential for further biological study." @default.
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- W2017860706 date "2009-02-01" @default.
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- W2017860706 title "A road less traveled by: Exploring a decade of Ellman chemistry" @default.
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- W2017860706 doi "https://doi.org/10.1016/j.bmc.2008.02.087" @default.
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