Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017861745> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2017861745 endingPage "258" @default.
- W2017861745 startingPage "251" @default.
- W2017861745 abstract "Small numbers of rat erythrocytes infected with viable P. berghei, when inoculated into susceptible rats together with hyperimmune rat serum (HIS), are fully neutralized. Serum from convalescent rats delays the onset of patency but does not neutralize. The neutralizing efficiency of HIS rises in proportion to the number of successive reinoculations of hyperimmune rats. In contrast, mice inoculated with parasites together with either HIS or normal rat serum succumbed to the disease at the same time after inoculation. Neutralization in rats occurs in vivo and is completed within 22 hours of inoculation. Much larger amounts of HIS are needed to achieve neutralization in splenectomized recipients than in intact rats. The action of HIS is dose-dependent. Thus, the degree of suppression of parasitaemia is proportional to the dose of HIS, while the mortality rate is inversely proportional to the dose. Suboptimal doses may even enhance the infection of recipient rats. The ability to produce neutralizing antibody is dissimilar in two strains of rat. Thus, the outbred Sabra strain produces neutralizing HIS, while the inbred Lewis rat is incapable of producing perceptible neutralizing antibody in our experimental model." @default.
- W2017861745 created "2016-06-24" @default.
- W2017861745 creator A5001454080 @default.
- W2017861745 creator A5005451509 @default.
- W2017861745 creator A5068231489 @default.
- W2017861745 date "1975-01-01" @default.
- W2017861745 modified "2023-09-27" @default.
- W2017861745 title "Neutralizing antibody in rodent malaria" @default.
- W2017861745 cites W1991004260 @default.
- W2017861745 cites W2023747716 @default.
- W2017861745 cites W2053308624 @default.
- W2017861745 cites W2329350711 @default.
- W2017861745 cites W2332998286 @default.
- W2017861745 cites W2418732695 @default.
- W2017861745 doi "https://doi.org/10.1016/0035-9203(75)90164-9" @default.
- W2017861745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1101458" @default.
- W2017861745 hasPublicationYear "1975" @default.
- W2017861745 type Work @default.
- W2017861745 sameAs 2017861745 @default.
- W2017861745 citedByCount "18" @default.
- W2017861745 countsByYear W20178617452014 @default.
- W2017861745 crossrefType "journal-article" @default.
- W2017861745 hasAuthorship W2017861745A5001454080 @default.
- W2017861745 hasAuthorship W2017861745A5005451509 @default.
- W2017861745 hasAuthorship W2017861745A5068231489 @default.
- W2017861745 hasConcept C14086860 @default.
- W2017861745 hasConcept C150903083 @default.
- W2017861745 hasConcept C159047783 @default.
- W2017861745 hasConcept C159654299 @default.
- W2017861745 hasConcept C180032290 @default.
- W2017861745 hasConcept C203014093 @default.
- W2017861745 hasConcept C207001950 @default.
- W2017861745 hasConcept C2777237215 @default.
- W2017861745 hasConcept C2778048844 @default.
- W2017861745 hasConcept C2779261636 @default.
- W2017861745 hasConcept C3018913218 @default.
- W2017861745 hasConcept C86803240 @default.
- W2017861745 hasConceptScore W2017861745C14086860 @default.
- W2017861745 hasConceptScore W2017861745C150903083 @default.
- W2017861745 hasConceptScore W2017861745C159047783 @default.
- W2017861745 hasConceptScore W2017861745C159654299 @default.
- W2017861745 hasConceptScore W2017861745C180032290 @default.
- W2017861745 hasConceptScore W2017861745C203014093 @default.
- W2017861745 hasConceptScore W2017861745C207001950 @default.
- W2017861745 hasConceptScore W2017861745C2777237215 @default.
- W2017861745 hasConceptScore W2017861745C2778048844 @default.
- W2017861745 hasConceptScore W2017861745C2779261636 @default.
- W2017861745 hasConceptScore W2017861745C3018913218 @default.
- W2017861745 hasConceptScore W2017861745C86803240 @default.
- W2017861745 hasIssue "2" @default.
- W2017861745 hasLocation W20178617451 @default.
- W2017861745 hasLocation W20178617452 @default.
- W2017861745 hasOpenAccess W2017861745 @default.
- W2017861745 hasPrimaryLocation W20178617451 @default.
- W2017861745 hasRelatedWork W1972745941 @default.
- W2017861745 hasRelatedWork W1982191541 @default.
- W2017861745 hasRelatedWork W2002414632 @default.
- W2017861745 hasRelatedWork W2017861745 @default.
- W2017861745 hasRelatedWork W2043102346 @default.
- W2017861745 hasRelatedWork W2054563937 @default.
- W2017861745 hasRelatedWork W2076366830 @default.
- W2017861745 hasRelatedWork W2126654882 @default.
- W2017861745 hasRelatedWork W2132089352 @default.
- W2017861745 hasRelatedWork W2165262752 @default.
- W2017861745 hasVolume "69" @default.
- W2017861745 isParatext "false" @default.
- W2017861745 isRetracted "false" @default.
- W2017861745 magId "2017861745" @default.
- W2017861745 workType "article" @default.