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- W2017874118 abstract "Abstract By affinity chromatography on agarose-fixed fibrinogen (FG-ag) soluble fibrin can be isolated from plasma samples or aqueous solutions and quantified by radio-activity measurement or by the staphylococcal clumping test. Using radiolabelled fibrinogen for the insolubilization it could be shown that the FG-ag column is stable and is not degraded even after many runs of plasma samples over a long period of time. By addition of radioactive fibrinogen and fibrin to plasma samples standardized and reproducible conditions are established for clinical use of the method. The amount of soluble fibrin in normal donors was found to be about 0.6 - 0.7 mg%. An elevated fibrin concentration up to 6 mg% above the normal value was detected in plasma of patients after myocardial infarction, even when the coagulation parameters were still normal." @default.
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- W2017874118 date "1977-03-01" @default.
- W2017874118 modified "2023-09-27" @default.
- W2017874118 title "Affinity chromatography and quantitation of soluble fibrin from plasma" @default.
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- W2017874118 doi "https://doi.org/10.1016/0049-3848(77)90148-7" @default.
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