FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017875777> ?p ?o ?g. }

• W2017875777 endingPage "483" @default.
• W2017875777 startingPage "467" @default.
• W2017875777 abstract "The tRNA anticodon loops always comprise seven nucleotides and is involved in many recognition processes with proteins and RNA fragments. We have investigated the nature and the possible interactions between the first (32) and last (38) residues of the loop on the basis of the available sequences and crystal structures. The data demonstrate the conservation of a bifurcated hydrogen bond interaction between residues 32 and 38, located at the stem/loop junction. This interaction leads to the formation of a non-canonical base-pair which is preserved in the known crystal structures of tRNA/synthetase complexes. Among the tRNA and tDNA sequences, 93 % of the 32.38 oppositions can be assigned to two families of isosteric base-pairs, one with a large (86 %) and the other with a much smaller (7 %) population. The remainder (7 %) of the oppositions have been assigned to a third family due to the lack of evidence for assigning them into the first two sets. In all families, the Y32.R38 base-pairs are not isosteric upon reversal (like the sheared G.A or wobble G.U pairs), explaining the strong conservation of a pyrimidine at position 32. Thus, the 32.38 interaction extends the sequence signature of the anticodon loop beyond the conserved U-turn at position 33 and the usually modified purine at position 37. A comparison with other loops containing both a singly hydrogen-bonded base-pair and a U-turn suggests that the 32.38 pair could be involved in the formation of a base triple with a residue in a ribosomal RNA component. It is also observed that two crystal structures of ribozymes (hammerhead and leadzyme) present similar base-pairs at the cleavage site." @default.
• W2017875777 created "2016-06-24" @default.
• W2017875777 creator A5018416560 @default.
• W2017875777 creator A5049661679 @default.
• W2017875777 date "1999-09-01" @default.
• W2017875777 modified "2023-10-14" @default.
• W2017875777 title "Singly and Bifurcated Hydrogen-bonded Base-pairs in tRNA Anticodon Hairpins and Ribozymes" @default.
• W2017875777 cites W1543558622 @default.
• W2017875777 cites W1569125732 @default.
• W2017875777 cites W1595094981 @default.
• W2017875777 cites W1597533137 @default.
• W2017875777 cites W1822012546 @default.
• W2017875777 cites W1950941644 @default.
• W2017875777 cites W1964504545 @default.
• W2017875777 cites W1969758655 @default.
• W2017875777 cites W1970209499 @default.
• W2017875777 cites W1970318593 @default.
• W2017875777 cites W1982117955 @default.
• W2017875777 cites W1985122290 @default.
• W2017875777 cites W1993926172 @default.
• W2017875777 cites W2000064612 @default.
• W2017875777 cites W2003049655 @default.
• W2017875777 cites W2003122343 @default.
• W2017875777 cites W2005420540 @default.
• W2017875777 cites W2011493287 @default.
• W2017875777 cites W2021320387 @default.
• W2017875777 cites W2022221430 @default.
• W2017875777 cites W2022838319 @default.
• W2017875777 cites W2023668225 @default.
• W2017875777 cites W2024059257 @default.
• W2017875777 cites W2026817175 @default.
• W2017875777 cites W2027042879 @default.
• W2017875777 cites W2027821476 @default.
• W2017875777 cites W2031281236 @default.
• W2017875777 cites W2034336251 @default.
• W2017875777 cites W2035783320 @default.
• W2017875777 cites W2036683766 @default.
• W2017875777 cites W2038545035 @default.
• W2017875777 cites W2044247083 @default.
• W2017875777 cites W2050560798 @default.
• W2017875777 cites W2057892106 @default.
• W2017875777 cites W2060250925 @default.
• W2017875777 cites W2060658020 @default.
• W2017875777 cites W2063933849 @default.
• W2017875777 cites W2072737163 @default.
• W2017875777 cites W2072933083 @default.
• W2017875777 cites W2074589414 @default.
• W2017875777 cites W2079745606 @default.
• W2017875777 cites W2081125994 @default.
• W2017875777 cites W2082063162 @default.
• W2017875777 cites W2082882553 @default.
• W2017875777 cites W2082942098 @default.
• W2017875777 cites W2085158278 @default.
• W2017875777 cites W2085791091 @default.
• W2017875777 cites W2092011244 @default.
• W2017875777 cites W2092221199 @default.
• W2017875777 cites W2093109164 @default.
• W2017875777 cites W2094853570 @default.
• W2017875777 cites W2099029772 @default.
• W2017875777 cites W2102683170 @default.
• W2017875777 cites W2125931595 @default.
• W2017875777 cites W2129210977 @default.
• W2017875777 cites W2133324564 @default.
• W2017875777 cites W2133962138 @default.
• W2017875777 cites W2138489013 @default.
• W2017875777 cites W2139305314 @default.
• W2017875777 cites W2139377935 @default.
• W2017875777 cites W2139629312 @default.
• W2017875777 cites W2148580376 @default.
• W2017875777 cites W2164783818 @default.
• W2017875777 cites W2191263811 @default.
• W2017875777 cites W3027098865 @default.
• W2017875777 cites W319682455 @default.
• W2017875777 cites W333518702 @default.
• W2017875777 cites W4234887284 @default.
• W2017875777 doi "https://doi.org/10.1006/jmbi.1999.3080" @default.
• W2017875777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10497015" @default.
• W2017875777 hasPublicationYear "1999" @default.
• W2017875777 type Work @default.
• W2017875777 sameAs 2017875777 @default.
• W2017875777 citedByCount "110" @default.
• W2017875777 countsByYear W20178757772012 @default.
• W2017875777 countsByYear W20178757772013 @default.
• W2017875777 countsByYear W20178757772014 @default.
• W2017875777 countsByYear W20178757772016 @default.
• W2017875777 countsByYear W20178757772017 @default.
• W2017875777 countsByYear W20178757772018 @default.
• W2017875777 countsByYear W20178757772019 @default.
• W2017875777 countsByYear W20178757772020 @default.
• W2017875777 countsByYear W20178757772021 @default.
• W2017875777 countsByYear W20178757772022 @default.
• W2017875777 countsByYear W20178757772023 @default.
• W2017875777 crossrefType "journal-article" @default.
• W2017875777 hasAuthorship W2017875777A5018416560 @default.
• W2017875777 hasAuthorship W2017875777A5049661679 @default.
• W2017875777 hasConcept C104317684 @default.
• W2017875777 hasConcept C112887158 @default.
• W2017875777 hasConcept C121332964 @default.

• next