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- W2017942937 abstract "Sodium fluoroacetate is known as compound 1080; it was discovered by the German chemicals during World War II. It is a compound soluble in water, odorless and tasteless. The lethal dose 50 in humans is 2 to 4 mg/kg. Because of its lethality, it has been recalled in several countries including Colombia. This compound causes biochemical and physiological effects as citrate accumulation, altered mitochondrial Citrate transporter, the accumulation of lactic acid, impaired glucose regulation and hidroelectrolyte disorders (mainly calcium disturbances). The clinical manifestations of poisoning by this substance are non-specific, which males their identificacion and treatment difficult, making it to increase its lethality. Ethanol increases the level of acetat, thus providing an alternative substrate Krebs cycle and may offer benefits in the acute treatment of these patients; however, management support is the mainstay of management of these cases. Here it is reported a case of intentional ingestion in an adolescent, with delayed diagnosis a successful outcome." @default.
- W2017942937 created "2016-06-24" @default.
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- W2017942937 date "2014-05-30" @default.
- W2017942937 modified "2023-09-27" @default.
- W2017942937 title "Intoxicación por fluoroacetato de sodio" @default.
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- W2017942937 doi "https://doi.org/10.15446/revfacmed.v62n1.43781" @default.
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