FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017954966> ?p ?o ?g. }

• W2017954966 endingPage "96" @default.
• W2017954966 startingPage "83" @default.
• W2017954966 abstract "The origin of membraneous structures in the cytoplasm of human erythrocytes infected with the malaria parasite, Plasmodium falciparum, was determined by confocal fluorescence imaging microscopy. When infectious merozoites invaded erythrocytes labeled with the fluorescent, lipophilic, non-exchangeable molecules DiIC16 or DiOC16, a ring of fluorescence was observed surrounding the internal parasite, indicating that the parasitophorous vacuolar membrane (PVM) is formed in part from the erythrocyte membrane. As the parasites matured, fluorescent vesicles were seen to be exported into the erythrocyte cytoplasm, beginning at 6 h post-invasion. During intraerythrocytic development, these dyes were transferred from the PVM to the parasite. When fluorescently labeled merozoites were released from these cells and invaded unlabeled erythrocytes, fluorescence was confined to the parasite throughout the entire erythrocytic cycle. Taken together, these results demonstrate that all vesicles/membranous compartments in the erythrocyte cytoplasm of parasitized erythrocytes (IRBC) contain membrane derived from the PVM. Based on this information, we define pathways that the parasite utilizes to export proteins and lipids to the host cell cytoplasm and surface membrane. When IRBC were labeled post-invasion with DiIC16 or DiOC16 and the parasites allowed to mature for one life cycle, the dyes were confined to the erythrocyte membrane, demonstrating that the host cell membrane of IRBC does not endocytose and there is no membrane exchange from the erythrocyte to the parasite. This investigation helps to resolve two long-standing controversies and provides new insights into the transport pathways that malaria parasites utilize during their development within host erythrocytes." @default.
• W2017954966 created "2016-06-24" @default.
• W2017954966 creator A5002197159 @default.
• W2017954966 creator A5018924790 @default.
• W2017954966 creator A5074768077 @default.
• W2017954966 date "1994-07-01" @default.
• W2017954966 modified "2023-09-24" @default.
• W2017954966 title "Characterization of trafficking pathways and membrane genesis in malaria-infected erythrocytes" @default.
• W2017954966 cites W1844745998 @default.
• W2017954966 cites W1855353753 @default.
• W2017954966 cites W191400563 @default.
• W2017954966 cites W1966624722 @default.
• W2017954966 cites W1969503178 @default.
• W2017954966 cites W1972440123 @default.
• W2017954966 cites W1973589145 @default.
• W2017954966 cites W1993733633 @default.
• W2017954966 cites W1995211705 @default.
• W2017954966 cites W2002918123 @default.
• W2017954966 cites W2014419556 @default.
• W2017954966 cites W2020251171 @default.
• W2017954966 cites W2025708808 @default.
• W2017954966 cites W2029365127 @default.
• W2017954966 cites W2031089555 @default.
• W2017954966 cites W2032585602 @default.
• W2017954966 cites W2034886626 @default.
• W2017954966 cites W2038251648 @default.
• W2017954966 cites W2041539272 @default.
• W2017954966 cites W2056783293 @default.
• W2017954966 cites W2056907361 @default.
• W2017954966 cites W2063059714 @default.
• W2017954966 cites W2085670265 @default.
• W2017954966 cites W2086983202 @default.
• W2017954966 cites W2088046332 @default.
• W2017954966 cites W2100326823 @default.
• W2017954966 cites W2107193406 @default.
• W2017954966 cites W2119329557 @default.
• W2017954966 cites W2126727152 @default.
• W2017954966 cites W2129167229 @default.
• W2017954966 cites W2135067367 @default.
• W2017954966 cites W2155421201 @default.
• W2017954966 cites W2155966745 @default.
• W2017954966 cites W2168163975 @default.
• W2017954966 cites W2186323236 @default.
• W2017954966 cites W2325256638 @default.
• W2017954966 cites W2406760893 @default.
• W2017954966 cites W2410388523 @default.
• W2017954966 cites W2414308396 @default.
• W2017954966 doi "https://doi.org/10.1016/0166-6851(94)90038-8" @default.
• W2017954966 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7984190" @default.
• W2017954966 hasPublicationYear "1994" @default.
• W2017954966 type Work @default.
• W2017954966 sameAs 2017954966 @default.
• W2017954966 citedByCount "50" @default.
• W2017954966 countsByYear W20179549662013 @default.
• W2017954966 countsByYear W20179549662016 @default.
• W2017954966 countsByYear W20179549662018 @default.
• W2017954966 countsByYear W20179549662019 @default.
• W2017954966 countsByYear W20179549662020 @default.
• W2017954966 crossrefType "journal-article" @default.
• W2017954966 hasAuthorship W2017954966A5002197159 @default.
• W2017954966 hasAuthorship W2017954966A5018924790 @default.
• W2017954966 hasAuthorship W2017954966A5074768077 @default.
• W2017954966 hasConcept C121332964 @default.
• W2017954966 hasConcept C130316041 @default.
• W2017954966 hasConcept C136764020 @default.
• W2017954966 hasConcept C169274487 @default.
• W2017954966 hasConcept C190062978 @default.
• W2017954966 hasConcept C203014093 @default.
• W2017954966 hasConcept C2776557347 @default.
• W2017954966 hasConcept C2778048844 @default.
• W2017954966 hasConcept C2778371730 @default.
• W2017954966 hasConcept C2778675580 @default.
• W2017954966 hasConcept C2779178360 @default.
• W2017954966 hasConcept C41008148 @default.
• W2017954966 hasConcept C41625074 @default.
• W2017954966 hasConcept C55493867 @default.
• W2017954966 hasConcept C62520636 @default.
• W2017954966 hasConcept C71928629 @default.
• W2017954966 hasConcept C86803240 @default.
• W2017954966 hasConcept C91881484 @default.
• W2017954966 hasConcept C95444343 @default.
• W2017954966 hasConceptScore W2017954966C121332964 @default.
• W2017954966 hasConceptScore W2017954966C130316041 @default.
• W2017954966 hasConceptScore W2017954966C136764020 @default.
• W2017954966 hasConceptScore W2017954966C169274487 @default.
• W2017954966 hasConceptScore W2017954966C190062978 @default.
• W2017954966 hasConceptScore W2017954966C203014093 @default.
• W2017954966 hasConceptScore W2017954966C2776557347 @default.
• W2017954966 hasConceptScore W2017954966C2778048844 @default.
• W2017954966 hasConceptScore W2017954966C2778371730 @default.
• W2017954966 hasConceptScore W2017954966C2778675580 @default.
• W2017954966 hasConceptScore W2017954966C2779178360 @default.
• W2017954966 hasConceptScore W2017954966C41008148 @default.
• W2017954966 hasConceptScore W2017954966C41625074 @default.
• W2017954966 hasConceptScore W2017954966C55493867 @default.
• W2017954966 hasConceptScore W2017954966C62520636 @default.
• W2017954966 hasConceptScore W2017954966C71928629 @default.
• W2017954966 hasConceptScore W2017954966C86803240 @default.

• next