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• W2017961366 startingPage "1011" @default.
• W2017961366 abstract "The EGS4 Monte Carlo radiation transport code was used to systematically study the dose perturbation near planar and cylindrical air cavities in a water medium irradiated by megavoltage x‐ray beams. The variables of the problem included x‐ray energy, cavity shape and dimension, and depth of the cavity in water. The Monte Carlo code was initially validated against published measurements and its results were found to agree within 2% with the published measurements. The study results indicate that the dose perturbation is strongly dependent on x‐ray energy, field size, depth, and size of cavity in water. For example, the Monte Carlo calculations show dose reductions of 42% and 18% at 0.05 and 2 mm, respectively, beyond the air–water interface distal to the radiation source for a 3 cm thick air slab irradiated by a single 5×5 cm 2 15 MV beam. The dose reductions are smaller for a parallel‐opposed pair of 5×5 cm 2 15 MV x‐ray beams, being 21% and 11% for the same depths. The combined set of Monte Carlo calculations showed that the dose reduction near an air cavity is greater for: (a) Smaller x‐ray field size, (b) higher x‐ray energy, (c) larger air‐cavity size, and (d) smaller depth in water where the air cavity is situated. A potential clinical application of these results to the treatment of prostate cancer is discussed." @default.
• W2017961366 created "2016-06-24" @default.
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• W2017961366 date "2000-05-01" @default.
• W2017961366 modified "2023-09-25" @default.
• W2017961366 title "A systematic evaluation of air cavity dose perturbation in megavoltage x-ray beams" @default.
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• W2017961366 doi "https://doi.org/10.1118/1.598966" @default.
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