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- W2017991002 abstract "Rarely are investigators so bold as to produce disease in man, but in the field of infectious diseases they have done so repeatedly. Often these diseases were mild, usually they were self-limited, and sometimes they could be cured with drugs; yet the subject of the experiment always ran some risk of disability or death. Since exposing men to such hazards contrasts sharply with the concepts of human dignity embodied in Judeo-Christian ethics, it is interesting to see how these concepts affected the evolution of human experimentation. The surge of scientific discovery during the Renaissance and early modern period involved mostly inanimate objects at first and later animals. The thread of experimentation on humans can be picked up easily in 1721 when a smallpox epidemic was raging in London. George I, loath to have his grandchildren inoculated as recommended by Lady Mary Montagu, ordered the virus given first to six condemned" @default.
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- W2017991002 date "1966-11-28" @default.
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- W2017991002 title "Human Experimentation in Infectious Diseases" @default.
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- W2017991002 doi "https://doi.org/10.1001/jama.1966.03110220081028" @default.
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