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- W2017997600 abstract "Anti-Tac monoclonal antibody has been identified as a putative antibody against the receptor for T-cell growth factor (TCGF). We now show that: (i) TCGF blocks 85% of 3H-labeled anti-Tac binding to phytohemagglutinin-activated lymphoblasts and (ii) both anti-Tac and anti-TCGF immunoprecipitate a protein band that appears to represent TCGF crosslinked to its receptor on HUT-102B2 cells. In HUT-102B2 cells, the TCGF receptor is a Mr 50,000 glycoprotein with internal disulfide bond(s) and a pI of 5.5-6.0, and it represents approximately equal to 0.05% of total cellular de novo protein synthesis. It contains a peptide of Mr 33,000 that is processed to a mature form that includes N-linked and O-linked sugars and sialic acid." @default.
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- W2017997600 date "1983-11-01" @default.
- W2017997600 modified "2023-09-25" @default.
- W2017997600 title "Characterization of the human receptor for T-cell growth factor." @default.
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- W2017997600 doi "https://doi.org/10.1073/pnas.80.22.6957" @default.
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