Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018008596> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2018008596 endingPage "4670" @default.
- W2018008596 startingPage "4662" @default.
- W2018008596 abstract "In the present study proteomes of liver samples were analyzed after administration of phenobarbital (PB) or 3-methylcholantrene (3-MC) to mice. Liver cell homogenates were subfractionated by differential ultracentrifugation into cytosol and microsomes, which were subjected to 2-DE to generate the proteomic maps of these fractions. 2-DE yielded 1100 and 800 protein spots for microsomes and cytosol, respectively. General trends of the fraction-specific alterations after 3-MC or PB treatment were evaluated using the Student's t-test and the principal component analysis (PCA). According to the PCA-derived data, the microsomal changes after 3-MC and PB treatment were quite similar. However, in the case of the cytosol data, the specificities of 3-MC- and PB-induced responses could be clearly distinguished from each other. Protein spots, whose expression levels differed from control, were identified by MALDI-TOF PMF. Proteomic studies such as those reported herein can be useful in identifying the molecular-based toxicity of lead drug candidates." @default.
- W2018008596 created "2016-06-24" @default.
- W2018008596 creator A5008379974 @default.
- W2018008596 creator A5043001741 @default.
- W2018008596 creator A5044264441 @default.
- W2018008596 creator A5053010793 @default.
- W2018008596 creator A5057360805 @default.
- W2018008596 creator A5059251330 @default.
- W2018008596 date "2006-08-01" @default.
- W2018008596 modified "2023-09-27" @default.
- W2018008596 title "Proteomic profiles of induced hepatotoxicity at the subcellular level" @default.
- W2018008596 cites W118891992 @default.
- W2018008596 cites W1972854982 @default.
- W2018008596 cites W1996524127 @default.
- W2018008596 cites W2016271327 @default.
- W2018008596 cites W2019109379 @default.
- W2018008596 cites W2034627568 @default.
- W2018008596 cites W2038657917 @default.
- W2018008596 cites W2050819672 @default.
- W2018008596 cites W2078594804 @default.
- W2018008596 cites W2083287953 @default.
- W2018008596 cites W2107363136 @default.
- W2018008596 cites W2118577784 @default.
- W2018008596 cites W2128772465 @default.
- W2018008596 cites W2130106768 @default.
- W2018008596 cites W2132777822 @default.
- W2018008596 cites W2135248587 @default.
- W2018008596 cites W2139217093 @default.
- W2018008596 cites W2143194676 @default.
- W2018008596 cites W2157062461 @default.
- W2018008596 cites W2283883132 @default.
- W2018008596 cites W4232534952 @default.
- W2018008596 doi "https://doi.org/10.1002/pmic.200600342" @default.
- W2018008596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16897686" @default.
- W2018008596 hasPublicationYear "2006" @default.
- W2018008596 type Work @default.
- W2018008596 sameAs 2018008596 @default.
- W2018008596 citedByCount "19" @default.
- W2018008596 countsByYear W20180085962012 @default.
- W2018008596 countsByYear W20180085962020 @default.
- W2018008596 countsByYear W20180085962021 @default.
- W2018008596 countsByYear W20180085962022 @default.
- W2018008596 crossrefType "journal-article" @default.
- W2018008596 hasAuthorship W2018008596A5008379974 @default.
- W2018008596 hasAuthorship W2018008596A5043001741 @default.
- W2018008596 hasAuthorship W2018008596A5044264441 @default.
- W2018008596 hasAuthorship W2018008596A5053010793 @default.
- W2018008596 hasAuthorship W2018008596A5057360805 @default.
- W2018008596 hasAuthorship W2018008596A5059251330 @default.
- W2018008596 hasConcept C104317684 @default.
- W2018008596 hasConcept C104397665 @default.
- W2018008596 hasConcept C181199279 @default.
- W2018008596 hasConcept C185592680 @default.
- W2018008596 hasConcept C2778793413 @default.
- W2018008596 hasConcept C46111723 @default.
- W2018008596 hasConcept C54689828 @default.
- W2018008596 hasConcept C55493867 @default.
- W2018008596 hasConcept C86803240 @default.
- W2018008596 hasConcept C87644729 @default.
- W2018008596 hasConcept C98274493 @default.
- W2018008596 hasConcept C98539663 @default.
- W2018008596 hasConceptScore W2018008596C104317684 @default.
- W2018008596 hasConceptScore W2018008596C104397665 @default.
- W2018008596 hasConceptScore W2018008596C181199279 @default.
- W2018008596 hasConceptScore W2018008596C185592680 @default.
- W2018008596 hasConceptScore W2018008596C2778793413 @default.
- W2018008596 hasConceptScore W2018008596C46111723 @default.
- W2018008596 hasConceptScore W2018008596C54689828 @default.
- W2018008596 hasConceptScore W2018008596C55493867 @default.
- W2018008596 hasConceptScore W2018008596C86803240 @default.
- W2018008596 hasConceptScore W2018008596C87644729 @default.
- W2018008596 hasConceptScore W2018008596C98274493 @default.
- W2018008596 hasConceptScore W2018008596C98539663 @default.
- W2018008596 hasIssue "16" @default.
- W2018008596 hasLocation W20180085961 @default.
- W2018008596 hasLocation W20180085962 @default.
- W2018008596 hasOpenAccess W2018008596 @default.
- W2018008596 hasPrimaryLocation W20180085961 @default.
- W2018008596 hasRelatedWork W1697546316 @default.
- W2018008596 hasRelatedWork W1975019729 @default.
- W2018008596 hasRelatedWork W1977200340 @default.
- W2018008596 hasRelatedWork W2018008596 @default.
- W2018008596 hasRelatedWork W2034933779 @default.
- W2018008596 hasRelatedWork W2049192520 @default.
- W2018008596 hasRelatedWork W2081562851 @default.
- W2018008596 hasRelatedWork W2083070772 @default.
- W2018008596 hasRelatedWork W2162721069 @default.
- W2018008596 hasRelatedWork W48042620 @default.
- W2018008596 hasVolume "6" @default.
- W2018008596 isParatext "false" @default.
- W2018008596 isRetracted "false" @default.
- W2018008596 magId "2018008596" @default.
- W2018008596 workType "article" @default.