FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018009871> ?p ?o ?g. }

• W2018009871 endingPage "480" @default.
• W2018009871 startingPage "473" @default.
• W2018009871 abstract "Objectives. Prostate-specific antigen (PSA) is produced exclusively in the prostate gland and is currently the most useful clinical marker for the detection of prostate cancer. In this report, we examine whether serum PSA is also a predictor of important benign prostatic hyperplasia (BPH)-related outcomes, acute urinary retention (AUR), and the need for BPH-related surgery. Methods. Three thousand forty men were treated with either placebo or finasteride in a double-blind, randomized study of 4-year duration. Serum PSA was measured at baseline, and baseline prostate volume was measured in a 10% subset of 312 men. Probabilities and cumulative incidences of AUR and BPH-related surgery, as well as reduction in risk of events with finasteride, were calculated for the entire patient population, stratified by treatment assignment, baseline serum PSA, and prostate volume. Results. The risk of either needing BPH-related surgery or developing AUR ranged from 8.9% to 22.0% during the 4 years in placebo-treated patients stratified by increasing prostate volume and from 7.8% to 19.9% when stratified by increasing serum PSA. In comparison with symptom scores, flow rates, and residual urine volume, receiver operating characteristic curve analyses showed that serum PSA and prostate volume were the most powerful predictors of spontaneous AUR in placebo-treated patients (area under the curve 0.70 and 0.81, respectively). Finasteride treatment reduced the relative risk of needing surgery or developing AUR by 50% to 74% and by 43% to 60% when stratified by increasing prostate volume and serum PSA, respectively. Conclusions. Serum PSA and prostate volume are powerful predictors of the risk of AUR and the need for BPH-related surgery in men with BPH. Knowledge of baseline serum PSA and/or prostate volume are useful tools to aid physicians and decision makers in predicting the risk of BPH-related outcomes and choosing therapy for BPH." @default.
• W2018009871 created "2016-06-24" @default.
• W2018009871 creator A5005637307 @default.
• W2018009871 creator A5006866144 @default.
• W2018009871 creator A5033244503 @default.
• W2018009871 creator A5036650187 @default.
• W2018009871 creator A5044758338 @default.
• W2018009871 creator A5049019006 @default.
• W2018009871 creator A5058375255 @default.
• W2018009871 creator A5071743263 @default.
• W2018009871 creator A5072587860 @default.
• W2018009871 creator A5077547822 @default.
• W2018009871 creator A5081214299 @default.
• W2018009871 creator A5087854382 @default.
• W2018009871 date "1999-03-01" @default.
• W2018009871 modified "2023-10-14" @default.
• W2018009871 title "Serum prostate-specific antigen concentration is a powerful predictor of acute urinary retention and need for surgery in men with clinical benign prostatic hyperplasia" @default.
• W2018009871 cites W1964130227 @default.
• W2018009871 cites W2002004951 @default.
• W2018009871 cites W2002658357 @default.
• W2018009871 cites W2011962188 @default.
• W2018009871 cites W2045486511 @default.
• W2018009871 cites W2082709973 @default.
• W2018009871 cites W2157825442 @default.
• W2018009871 cites W2247345803 @default.
• W2018009871 cites W2335425470 @default.
• W2018009871 cites W2804551733 @default.
• W2018009871 cites W4251816345 @default.
• W2018009871 doi "https://doi.org/10.1016/s0090-4295(98)00654-2" @default.
• W2018009871 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10096369" @default.
• W2018009871 hasPublicationYear "1999" @default.
• W2018009871 type Work @default.
• W2018009871 sameAs 2018009871 @default.
• W2018009871 citedByCount "311" @default.
• W2018009871 countsByYear W20180098712012 @default.
• W2018009871 countsByYear W20180098712013 @default.
• W2018009871 countsByYear W20180098712014 @default.
• W2018009871 countsByYear W20180098712015 @default.
• W2018009871 countsByYear W20180098712016 @default.
• W2018009871 countsByYear W20180098712017 @default.
• W2018009871 countsByYear W20180098712018 @default.
• W2018009871 countsByYear W20180098712019 @default.
• W2018009871 countsByYear W20180098712020 @default.
• W2018009871 countsByYear W20180098712021 @default.
• W2018009871 countsByYear W20180098712022 @default.
• W2018009871 countsByYear W20180098712023 @default.
• W2018009871 crossrefType "journal-article" @default.
• W2018009871 hasAuthorship W2018009871A5005637307 @default.
• W2018009871 hasAuthorship W2018009871A5006866144 @default.
• W2018009871 hasAuthorship W2018009871A5033244503 @default.
• W2018009871 hasAuthorship W2018009871A5036650187 @default.
• W2018009871 hasAuthorship W2018009871A5044758338 @default.
• W2018009871 hasAuthorship W2018009871A5049019006 @default.
• W2018009871 hasAuthorship W2018009871A5058375255 @default.
• W2018009871 hasAuthorship W2018009871A5071743263 @default.
• W2018009871 hasAuthorship W2018009871A5072587860 @default.
• W2018009871 hasAuthorship W2018009871A5077547822 @default.
• W2018009871 hasAuthorship W2018009871A5081214299 @default.
• W2018009871 hasAuthorship W2018009871A5087854382 @default.
• W2018009871 hasConcept C121608353 @default.
• W2018009871 hasConcept C126322002 @default.
• W2018009871 hasConcept C126894567 @default.
• W2018009871 hasConcept C142724271 @default.
• W2018009871 hasConcept C204787440 @default.
• W2018009871 hasConcept C27081682 @default.
• W2018009871 hasConcept C2775874879 @default.
• W2018009871 hasConcept C2776235491 @default.
• W2018009871 hasConcept C2777562237 @default.
• W2018009871 hasConcept C2779091618 @default.
• W2018009871 hasConcept C2780192828 @default.
• W2018009871 hasConcept C2780768273 @default.
• W2018009871 hasConcept C2781406297 @default.
• W2018009871 hasConcept C2908647359 @default.
• W2018009871 hasConcept C29456083 @default.
• W2018009871 hasConcept C71924100 @default.
• W2018009871 hasConcept C99454951 @default.
• W2018009871 hasConceptScore W2018009871C121608353 @default.
• W2018009871 hasConceptScore W2018009871C126322002 @default.
• W2018009871 hasConceptScore W2018009871C126894567 @default.
• W2018009871 hasConceptScore W2018009871C142724271 @default.
• W2018009871 hasConceptScore W2018009871C204787440 @default.
• W2018009871 hasConceptScore W2018009871C27081682 @default.
• W2018009871 hasConceptScore W2018009871C2775874879 @default.
• W2018009871 hasConceptScore W2018009871C2776235491 @default.
• W2018009871 hasConceptScore W2018009871C2777562237 @default.
• W2018009871 hasConceptScore W2018009871C2779091618 @default.
• W2018009871 hasConceptScore W2018009871C2780192828 @default.
• W2018009871 hasConceptScore W2018009871C2780768273 @default.
• W2018009871 hasConceptScore W2018009871C2781406297 @default.
• W2018009871 hasConceptScore W2018009871C2908647359 @default.
• W2018009871 hasConceptScore W2018009871C29456083 @default.
• W2018009871 hasConceptScore W2018009871C71924100 @default.
• W2018009871 hasConceptScore W2018009871C99454951 @default.
• W2018009871 hasIssue "3" @default.
• W2018009871 hasLocation W20180098711 @default.
• W2018009871 hasLocation W20180098712 @default.
• W2018009871 hasOpenAccess W2018009871 @default.
• W2018009871 hasPrimaryLocation W20180098711 @default.

• next