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- W2018011405 abstract "Activity of serotonergic dorsal raphe neurons was recorded intracellularly in a brainstem slice preparation from rats before and after local microperfusion of the neurotoxin 5,7-dihydroxytryptamine (5,7-DHT). The initial effect of the drug consisted of a transient hyperpolarization. Over 1-2 h after drug application there was a gradual decrease in efficacy of a hyperpolarizing current pulse to evoke a transient rectification. Also, action potentials in some cells failed to evoke a spike after-hyperpolarization. These effects are related to the neurodegenerative action of 5,7-DHT." @default.
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- W2018011405 date "1986-11-01" @default.
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- W2018011405 title "5,7-Dihydroxytryptamine modifies excitability of rat dorsal raphe serotonergic neurons in vitro" @default.
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- W2018011405 doi "https://doi.org/10.1016/0304-3940(86)90638-5" @default.
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