Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018016153> ?p ?o ?g. }
- W2018016153 endingPage "1295" @default.
- W2018016153 startingPage "1287" @default.
- W2018016153 abstract "Escherichia coli YjeE is a broadly conserved bacterial ATPase of unknown function that has been widely characterized as essential. Here, the transcriptional regulation of the promoter of yjeE (PyjeE) was probed using a luciferase reporter and 172 antibiotics of diverse mechanisms. Norfloxacin and other fluorquinolones were found to be the most potent activator of PyjeE through binding to DNA gyrase. The stimulation of PyjeE by norfloxacin was most impacted by lesions in two-component signal transduction systems with roles in respiration, central metabolism, and oxidative stress responses. This suggested that YjeE may have a critical role in aerobic metabolism. Remarkably, YjeE was found to be dispensable when cells were grown in the absence of oxygen. To the best of our knowledge, these findings represent the first definitive phenotypes for this enigmatic protein." @default.
- W2018016153 created "2016-06-24" @default.
- W2018016153 creator A5018622421 @default.
- W2018016153 creator A5076663151 @default.
- W2018016153 date "2008-12-01" @default.
- W2018016153 modified "2023-09-27" @default.
- W2018016153 title "Known Bioactive Small Molecules Probe the Function of a Widely Conserved but Enigmatic Bacterial ATPase, YjeE" @default.
- W2018016153 cites W1482770146 @default.
- W2018016153 cites W1586330996 @default.
- W2018016153 cites W1701180156 @default.
- W2018016153 cites W1910394702 @default.
- W2018016153 cites W1979700870 @default.
- W2018016153 cites W1988621565 @default.
- W2018016153 cites W1989446693 @default.
- W2018016153 cites W1989811570 @default.
- W2018016153 cites W1990453950 @default.
- W2018016153 cites W1990963283 @default.
- W2018016153 cites W1992889417 @default.
- W2018016153 cites W1997755659 @default.
- W2018016153 cites W2000323554 @default.
- W2018016153 cites W2002486322 @default.
- W2018016153 cites W2010577059 @default.
- W2018016153 cites W2023820135 @default.
- W2018016153 cites W2034475951 @default.
- W2018016153 cites W2051453478 @default.
- W2018016153 cites W2056098990 @default.
- W2018016153 cites W2057753478 @default.
- W2018016153 cites W2077167882 @default.
- W2018016153 cites W2081929574 @default.
- W2018016153 cites W2088880799 @default.
- W2018016153 cites W2099735662 @default.
- W2018016153 cites W2101322984 @default.
- W2018016153 cites W2110003576 @default.
- W2018016153 cites W2111967267 @default.
- W2018016153 cites W2112587413 @default.
- W2018016153 cites W2117087393 @default.
- W2018016153 cites W2125115802 @default.
- W2018016153 cites W2129634655 @default.
- W2018016153 cites W2135038276 @default.
- W2018016153 cites W2144281817 @default.
- W2018016153 cites W2146245198 @default.
- W2018016153 cites W2146288504 @default.
- W2018016153 cites W2146481325 @default.
- W2018016153 cites W2146538795 @default.
- W2018016153 cites W2147653566 @default.
- W2018016153 cites W2147776446 @default.
- W2018016153 cites W2153878038 @default.
- W2018016153 cites W2155266356 @default.
- W2018016153 cites W2155606054 @default.
- W2018016153 cites W2156369583 @default.
- W2018016153 cites W2157335840 @default.
- W2018016153 cites W2157652209 @default.
- W2018016153 cites W2158484542 @default.
- W2018016153 cites W2164997719 @default.
- W2018016153 cites W2165701675 @default.
- W2018016153 cites W2170455275 @default.
- W2018016153 cites W2171040994 @default.
- W2018016153 cites W2172196261 @default.
- W2018016153 cites W2172243413 @default.
- W2018016153 doi "https://doi.org/10.1016/j.chembiol.2008.10.007" @default.
- W2018016153 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19101473" @default.
- W2018016153 hasPublicationYear "2008" @default.
- W2018016153 type Work @default.
- W2018016153 sameAs 2018016153 @default.
- W2018016153 citedByCount "7" @default.
- W2018016153 countsByYear W20180161532012 @default.
- W2018016153 countsByYear W20180161532016 @default.
- W2018016153 countsByYear W20180161532017 @default.
- W2018016153 countsByYear W20180161532019 @default.
- W2018016153 countsByYear W20180161532021 @default.
- W2018016153 crossrefType "journal-article" @default.
- W2018016153 hasAuthorship W2018016153A5018622421 @default.
- W2018016153 hasAuthorship W2018016153A5076663151 @default.
- W2018016153 hasConcept C104317684 @default.
- W2018016153 hasConcept C14036430 @default.
- W2018016153 hasConcept C143065580 @default.
- W2018016153 hasConcept C167125095 @default.
- W2018016153 hasConcept C181199279 @default.
- W2018016153 hasConcept C23265538 @default.
- W2018016153 hasConcept C2778512257 @default.
- W2018016153 hasConcept C2778746504 @default.
- W2018016153 hasConcept C523546767 @default.
- W2018016153 hasConcept C54355233 @default.
- W2018016153 hasConcept C547475151 @default.
- W2018016153 hasConcept C55493867 @default.
- W2018016153 hasConcept C62478195 @default.
- W2018016153 hasConcept C86803240 @default.
- W2018016153 hasConcept C88045685 @default.
- W2018016153 hasConcept C95444343 @default.
- W2018016153 hasConceptScore W2018016153C104317684 @default.
- W2018016153 hasConceptScore W2018016153C14036430 @default.
- W2018016153 hasConceptScore W2018016153C143065580 @default.
- W2018016153 hasConceptScore W2018016153C167125095 @default.
- W2018016153 hasConceptScore W2018016153C181199279 @default.
- W2018016153 hasConceptScore W2018016153C23265538 @default.
- W2018016153 hasConceptScore W2018016153C2778512257 @default.
- W2018016153 hasConceptScore W2018016153C2778746504 @default.
- W2018016153 hasConceptScore W2018016153C523546767 @default.