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- W2018018047 abstract "We thank Drs Dimitrow and Undas for their interest and commentaries on our article regarding the impairment of von Willebrand factor (VWF) in the obstructive form of hypertrophic cardiomyopathy (HCM). We agree that spontaneous major bleedings were rare in our study despite the high frequency of acquired von Willebrand syndrome in patients with an obstructive form of HCM.1 In patients with aortic stenosis, cumulative evidence shows that VWF impairment (shear-stress-induced proteolysis of the largest multimers of VWF) favors or enhances spontaneous bleeding from a preexisting vascular lesion, mainly gastrointestinal angiodysplasia. …" @default.
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- W2018018047 date "2009-06-16" @default.
- W2018018047 modified "2023-10-18" @default.
- W2018018047 title "Response to Letter Regarding Article, “Functional Impairment of von Willebrand Factor in Hypertrophic Cardiomyopathy: Relation to Rest and Exercise Obstruction”" @default.
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- W2018018047 doi "https://doi.org/10.1161/circulationaha.108.843045" @default.
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