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- W2018019969 abstract "Abstract The effect of a low dose of omeprazole on intragastric acidity and fasting plasma gastrin concentration was measured in eight subjects with duodenal ulcer in remission. Intragastric acidity was measured during a baseline 24 h period. This was then repeated after 14 days of dosage with 10 mg of omeprazole administered daily, either in the morning or the evening, using a randomized, double-blind cross-over design. The median 24 h pH level rose significantly from a baseline of 1.6, to 3.1 and 3.5 during morning and evening dosages, respectively. However, variability in the response to this dose was substantial: three subjects exhibited no discernible change in 24 h median acidity on two occasions, while in others it was reduced by greater than 99%. Fasting plasma gastrin concentrations were not significantly altered by the administration of 10 mg of omeprazole daily for 2 weeks." @default.
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- W2018019969 date "1986-08-01" @default.
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- W2018019969 title "The effect of omeprazole on 24 h intragastric pH and fasting plasma gastrin during low dosage (10 mg) in the morning or the evening" @default.
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- W2018019969 doi "https://doi.org/10.1111/j.1440-1746.1986.tb00125.x" @default.
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