Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018045673> ?p ?o ?g. }
- W2018045673 endingPage "903" @default.
- W2018045673 startingPage "892" @default.
- W2018045673 abstract "Since the establishment of a canonical animal microRNA biogenesis pathway driven by the RNase III enzymes Drosha and Dicer, an unexpected variety of alternative mechanisms that generate functional microRNAs have emerged. We review here the many Drosha-independent and Dicer-independent microRNA biogenesis strategies characterized over the past few years. Beyond reflecting the flexibility of small RNA machineries, the existence of noncanonical pathways has consequences for interpreting mutants in the core microRNA machinery. Such mutants are commonly used to assess the consequences of total microRNA loss, and indeed, they exhibit many overall phenotypic similarities. Nevertheless, ongoing studies reveal a growing number of settings in which alternative microRNA pathways contribute to distinct phenotypes among core microRNA biogenesis mutants." @default.
- W2018045673 created "2016-06-24" @default.
- W2018045673 creator A5025956667 @default.
- W2018045673 creator A5048763567 @default.
- W2018045673 date "2011-09-01" @default.
- W2018045673 modified "2023-10-16" @default.
- W2018045673 title "Alternative miRNA Biogenesis Pathways and the Interpretation of Core miRNA Pathway Mutants" @default.
- W2018045673 cites W1499220571 @default.
- W2018045673 cites W1897385899 @default.
- W2018045673 cites W1964631913 @default.
- W2018045673 cites W1966185641 @default.
- W2018045673 cites W1966427699 @default.
- W2018045673 cites W1967884424 @default.
- W2018045673 cites W1968525732 @default.
- W2018045673 cites W1969003435 @default.
- W2018045673 cites W1969865366 @default.
- W2018045673 cites W1970064787 @default.
- W2018045673 cites W1970561408 @default.
- W2018045673 cites W1971099302 @default.
- W2018045673 cites W1974595624 @default.
- W2018045673 cites W1975336035 @default.
- W2018045673 cites W1980060544 @default.
- W2018045673 cites W1982250275 @default.
- W2018045673 cites W1985480639 @default.
- W2018045673 cites W1989015932 @default.
- W2018045673 cites W1991007428 @default.
- W2018045673 cites W1993841608 @default.
- W2018045673 cites W1998678099 @default.
- W2018045673 cites W2000912181 @default.
- W2018045673 cites W2003018477 @default.
- W2018045673 cites W2003207389 @default.
- W2018045673 cites W2004271888 @default.
- W2018045673 cites W2004280138 @default.
- W2018045673 cites W2005090326 @default.
- W2018045673 cites W2005625535 @default.
- W2018045673 cites W2007863176 @default.
- W2018045673 cites W2010890469 @default.
- W2018045673 cites W2013666461 @default.
- W2018045673 cites W2016038592 @default.
- W2018045673 cites W2022231987 @default.
- W2018045673 cites W2024829095 @default.
- W2018045673 cites W2029433700 @default.
- W2018045673 cites W2029955900 @default.
- W2018045673 cites W2030246519 @default.
- W2018045673 cites W2033518550 @default.
- W2018045673 cites W2034255392 @default.
- W2018045673 cites W2034793355 @default.
- W2018045673 cites W2036373513 @default.
- W2018045673 cites W2040058302 @default.
- W2018045673 cites W2042673698 @default.
- W2018045673 cites W2043030593 @default.
- W2018045673 cites W2045178946 @default.
- W2018045673 cites W2046486243 @default.
- W2018045673 cites W2049836150 @default.
- W2018045673 cites W2061664626 @default.
- W2018045673 cites W2062332984 @default.
- W2018045673 cites W2065602100 @default.
- W2018045673 cites W2066213138 @default.
- W2018045673 cites W2069085357 @default.
- W2018045673 cites W2069799979 @default.
- W2018045673 cites W2071925802 @default.
- W2018045673 cites W2072155079 @default.
- W2018045673 cites W2076560265 @default.
- W2018045673 cites W2076780294 @default.
- W2018045673 cites W2080551186 @default.
- W2018045673 cites W2085350682 @default.
- W2018045673 cites W2085841113 @default.
- W2018045673 cites W2088440342 @default.
- W2018045673 cites W2090226049 @default.
- W2018045673 cites W2094057862 @default.
- W2018045673 cites W2094786733 @default.
- W2018045673 cites W2100750972 @default.
- W2018045673 cites W2102111081 @default.
- W2018045673 cites W2106039274 @default.
- W2018045673 cites W2106142257 @default.
- W2018045673 cites W2112703265 @default.
- W2018045673 cites W2113934040 @default.
- W2018045673 cites W2113940243 @default.
- W2018045673 cites W2114012664 @default.
- W2018045673 cites W2115115731 @default.
- W2018045673 cites W2121196786 @default.
- W2018045673 cites W2124268899 @default.
- W2018045673 cites W2125939997 @default.
- W2018045673 cites W2129920669 @default.
- W2018045673 cites W2130993320 @default.
- W2018045673 cites W2131475898 @default.
- W2018045673 cites W2135710708 @default.
- W2018045673 cites W2137708006 @default.
- W2018045673 cites W2139074713 @default.
- W2018045673 cites W2139400461 @default.
- W2018045673 cites W2140166150 @default.
- W2018045673 cites W2140272588 @default.
- W2018045673 cites W2140446903 @default.
- W2018045673 cites W2142223308 @default.
- W2018045673 cites W2142515731 @default.
- W2018045673 cites W2143313547 @default.
- W2018045673 cites W2144717644 @default.
- W2018045673 cites W2147651981 @default.