FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018051708> ?p ?o ?g. }

• W2018051708 endingPage "7623" @default.
• W2018051708 startingPage "7618" @default.
• W2018051708 abstract "In this study it was demonstrated that the immunogenicity of Vi polysaccharide-diphtheria toxoid conjugates was related to the physical and chemical structure of the conjugate. Conjugates were prepared in two steps, firstly binding adipic acid dihydrazide (ADH) spacer molecules to diphtheria toxoid (DT) carrier protein then secondly binding varying amounts of this derivatized DT to a fixed amount of Vi capsular polysaccharide purified from Salmonella enterica Serovar Typhi. As the amount of DT bound to the Vi increased the size of the conjugate increased but also the degree of cross-linking increased. The immunogenicity of the conjugates was tested in mice and measured by ELISA for anti Vi and anti DT IgG responses, and the results revealed a trend that as the amount of DT bound to the Vi increased the anti Vi responses increased. This study establishes a correlation between physico-chemical characteristics of the conjugate and the magnitude of the anti Vi and anti DT responses." @default.
• W2018051708 created "2016-06-24" @default.
• W2018051708 creator A5020882704 @default.
• W2018051708 creator A5021947580 @default.
• W2018051708 creator A5022057431 @default.
• W2018051708 creator A5033554066 @default.
• W2018051708 creator A5045192254 @default.
• W2018051708 creator A5052033483 @default.
• W2018051708 creator A5053587866 @default.
• W2018051708 creator A5068236383 @default.
• W2018051708 creator A5077202050 @default.
• W2018051708 creator A5082632384 @default.
• W2018051708 date "2011-10-01" @default.
• W2018051708 modified "2023-09-25" @default.
• W2018051708 title "Physico-chemical properties of Salmonella typhi Vi polysaccharide–diphtheria toxoid conjugate vaccines affect immunogenicity" @default.
• W2018051708 cites W1515195345 @default.
• W2018051708 cites W1775749144 @default.
• W2018051708 cites W1810620487 @default.
• W2018051708 cites W1857703303 @default.
• W2018051708 cites W1966698951 @default.
• W2018051708 cites W1987692913 @default.
• W2018051708 cites W1988601139 @default.
• W2018051708 cites W1989524000 @default.
• W2018051708 cites W1996590652 @default.
• W2018051708 cites W1998738749 @default.
• W2018051708 cites W2021961709 @default.
• W2018051708 cites W2089052464 @default.
• W2018051708 cites W2090362268 @default.
• W2018051708 cites W2099752885 @default.
• W2018051708 cites W2107158542 @default.
• W2018051708 cites W2110447600 @default.
• W2018051708 cites W2115048812 @default.
• W2018051708 cites W2118314817 @default.
• W2018051708 cites W2130125439 @default.
• W2018051708 cites W2139075892 @default.
• W2018051708 cites W2164199104 @default.
• W2018051708 cites W2169253475 @default.
• W2018051708 doi "https://doi.org/10.1016/j.vaccine.2011.08.019" @default.
• W2018051708 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21843575" @default.
• W2018051708 hasPublicationYear "2011" @default.
• W2018051708 type Work @default.
• W2018051708 sameAs 2018051708 @default.
• W2018051708 citedByCount "24" @default.
• W2018051708 countsByYear W20180517082012 @default.
• W2018051708 countsByYear W20180517082013 @default.
• W2018051708 countsByYear W20180517082014 @default.
• W2018051708 countsByYear W20180517082015 @default.
• W2018051708 countsByYear W20180517082017 @default.
• W2018051708 countsByYear W20180517082018 @default.
• W2018051708 countsByYear W20180517082020 @default.
• W2018051708 countsByYear W20180517082021 @default.
• W2018051708 countsByYear W20180517082023 @default.
• W2018051708 crossrefType "journal-article" @default.
• W2018051708 hasAuthorship W2018051708A5020882704 @default.
• W2018051708 hasAuthorship W2018051708A5021947580 @default.
• W2018051708 hasAuthorship W2018051708A5022057431 @default.
• W2018051708 hasAuthorship W2018051708A5033554066 @default.
• W2018051708 hasAuthorship W2018051708A5045192254 @default.
• W2018051708 hasAuthorship W2018051708A5052033483 @default.
• W2018051708 hasAuthorship W2018051708A5053587866 @default.
• W2018051708 hasAuthorship W2018051708A5068236383 @default.
• W2018051708 hasAuthorship W2018051708A5077202050 @default.
• W2018051708 hasAuthorship W2018051708A5082632384 @default.
• W2018051708 hasConcept C100817775 @default.
• W2018051708 hasConcept C104317684 @default.
• W2018051708 hasConcept C134306372 @default.
• W2018051708 hasConcept C147483822 @default.
• W2018051708 hasConcept C159047783 @default.
• W2018051708 hasConcept C185592680 @default.
• W2018051708 hasConcept C197336794 @default.
• W2018051708 hasConcept C203014093 @default.
• W2018051708 hasConcept C22070199 @default.
• W2018051708 hasConcept C2777351567 @default.
• W2018051708 hasConcept C2777367657 @default.
• W2018051708 hasConcept C2779583294 @default.
• W2018051708 hasConcept C2780572238 @default.
• W2018051708 hasConcept C2780801004 @default.
• W2018051708 hasConcept C2780868878 @default.
• W2018051708 hasConcept C2994552716 @default.
• W2018051708 hasConcept C33057221 @default.
• W2018051708 hasConcept C33923547 @default.
• W2018051708 hasConcept C547475151 @default.
• W2018051708 hasConcept C55493867 @default.
• W2018051708 hasConcept C86803240 @default.
• W2018051708 hasConcept C89423630 @default.
• W2018051708 hasConceptScore W2018051708C100817775 @default.
• W2018051708 hasConceptScore W2018051708C104317684 @default.
• W2018051708 hasConceptScore W2018051708C134306372 @default.
• W2018051708 hasConceptScore W2018051708C147483822 @default.
• W2018051708 hasConceptScore W2018051708C159047783 @default.
• W2018051708 hasConceptScore W2018051708C185592680 @default.
• W2018051708 hasConceptScore W2018051708C197336794 @default.
• W2018051708 hasConceptScore W2018051708C203014093 @default.
• W2018051708 hasConceptScore W2018051708C22070199 @default.
• W2018051708 hasConceptScore W2018051708C2777351567 @default.
• W2018051708 hasConceptScore W2018051708C2777367657 @default.
• W2018051708 hasConceptScore W2018051708C2779583294 @default.
• W2018051708 hasConceptScore W2018051708C2780572238 @default.

• next