Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018053089> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2018053089 endingPage "327" @default.
- W2018053089 startingPage "321" @default.
- W2018053089 abstract "The purpose of the present study was to determine if electrocardiographic (EKG) changes observed in fetuses exposed in utero to ethylene glycol monomethyl ether (EGME) persisted beyond the fetal/neonatal period. Groups of pregnant Sprague-Dawley rats were gavaged on gestation days 7–13 (sperm = day 0) with 0, 50, or 75 mg/kg EGME. Body weight prior to delivery was reduced and gestation was prolonged in EGME-treated dams. EGME treatment reduced the percentage of pregnant dams that delivered, litter size, and pup weight. There were no survivors beyond 3 days of age in the 75 mg/kg EGME group. The number of litters surviving through weaning and weight gain of male and female offspring through 8 weeks of age were reduced in the 50 mg/kg EGME group. In this same group, heart weight was unaffected, but heart/body weight ratios were increased when rats were 8 weeks old. EKGs were obtained from unanesthetized and unrestrained rats at 3 and 6 weeks of age. Prenatal EGME exposure increased the QRS interval in 3- and 6-week-old rats, and increased the T wave in 6-week-old rats. Thirty-six and 54% of 3- and 6-week old litters, respectively, had one or more individuals that were classified as having an intraventricular conduction delay (double R wave and QRS interval of 14 msec or longer). No microscopic heart abnormalities were associated with the observed intraventricular conduction delay." @default.
- W2018053089 created "2016-06-24" @default.
- W2018053089 creator A5045087657 @default.
- W2018053089 creator A5046716366 @default.
- W2018053089 date "1988-09-01" @default.
- W2018053089 modified "2023-10-17" @default.
- W2018053089 title "Prenatal ethylene glycol monomethyl ether (EGME) exposure produces electrocardiographic changes in the rat" @default.
- W2018053089 cites W1975979630 @default.
- W2018053089 cites W1978328976 @default.
- W2018053089 cites W1980336264 @default.
- W2018053089 cites W2002528226 @default.
- W2018053089 cites W2023586439 @default.
- W2018053089 cites W2069020200 @default.
- W2018053089 cites W2078721583 @default.
- W2018053089 cites W2093401742 @default.
- W2018053089 doi "https://doi.org/10.1016/0041-008x(88)90168-8" @default.
- W2018053089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3420619" @default.
- W2018053089 hasPublicationYear "1988" @default.
- W2018053089 type Work @default.
- W2018053089 sameAs 2018053089 @default.
- W2018053089 citedByCount "11" @default.
- W2018053089 countsByYear W20180530892012 @default.
- W2018053089 countsByYear W20180530892015 @default.
- W2018053089 countsByYear W20180530892017 @default.
- W2018053089 crossrefType "journal-article" @default.
- W2018053089 hasAuthorship W2018053089A5045087657 @default.
- W2018053089 hasAuthorship W2018053089A5046716366 @default.
- W2018053089 hasConcept C111773187 @default.
- W2018053089 hasConcept C112672928 @default.
- W2018053089 hasConcept C126322002 @default.
- W2018053089 hasConcept C147583825 @default.
- W2018053089 hasConcept C172680121 @default.
- W2018053089 hasConcept C201614185 @default.
- W2018053089 hasConcept C2779234561 @default.
- W2018053089 hasConcept C2779429622 @default.
- W2018053089 hasConcept C2909091063 @default.
- W2018053089 hasConcept C3017863008 @default.
- W2018053089 hasConcept C42219234 @default.
- W2018053089 hasConcept C46973012 @default.
- W2018053089 hasConcept C54355233 @default.
- W2018053089 hasConcept C6557445 @default.
- W2018053089 hasConcept C71924100 @default.
- W2018053089 hasConcept C86803240 @default.
- W2018053089 hasConceptScore W2018053089C111773187 @default.
- W2018053089 hasConceptScore W2018053089C112672928 @default.
- W2018053089 hasConceptScore W2018053089C126322002 @default.
- W2018053089 hasConceptScore W2018053089C147583825 @default.
- W2018053089 hasConceptScore W2018053089C172680121 @default.
- W2018053089 hasConceptScore W2018053089C201614185 @default.
- W2018053089 hasConceptScore W2018053089C2779234561 @default.
- W2018053089 hasConceptScore W2018053089C2779429622 @default.
- W2018053089 hasConceptScore W2018053089C2909091063 @default.
- W2018053089 hasConceptScore W2018053089C3017863008 @default.
- W2018053089 hasConceptScore W2018053089C42219234 @default.
- W2018053089 hasConceptScore W2018053089C46973012 @default.
- W2018053089 hasConceptScore W2018053089C54355233 @default.
- W2018053089 hasConceptScore W2018053089C6557445 @default.
- W2018053089 hasConceptScore W2018053089C71924100 @default.
- W2018053089 hasConceptScore W2018053089C86803240 @default.
- W2018053089 hasIssue "2" @default.
- W2018053089 hasLocation W20180530891 @default.
- W2018053089 hasLocation W20180530892 @default.
- W2018053089 hasOpenAccess W2018053089 @default.
- W2018053089 hasPrimaryLocation W20180530891 @default.
- W2018053089 hasRelatedWork W122411500 @default.
- W2018053089 hasRelatedWork W1969825508 @default.
- W2018053089 hasRelatedWork W1970497695 @default.
- W2018053089 hasRelatedWork W1972381719 @default.
- W2018053089 hasRelatedWork W2000310418 @default.
- W2018053089 hasRelatedWork W2058666870 @default.
- W2018053089 hasRelatedWork W2122362363 @default.
- W2018053089 hasRelatedWork W2323075657 @default.
- W2018053089 hasRelatedWork W2325705545 @default.
- W2018053089 hasRelatedWork W2971464179 @default.
- W2018053089 hasVolume "95" @default.
- W2018053089 isParatext "false" @default.
- W2018053089 isRetracted "false" @default.
- W2018053089 magId "2018053089" @default.
- W2018053089 workType "article" @default.