Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018077130> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2018077130 endingPage "466" @default.
- W2018077130 startingPage "463" @default.
- W2018077130 abstract "Objective: To determine whether an antihistamine-decongestant combination (ADC) is superior to placebo in temporarily relieving symptoms of upper respiratory tract infection (URI) in preschool children. Design: Randomized, double-blind, placebo-controlled trial. Setting: Four pediatric offices in the Seattle, Wash., area. Participants: Children 6 months through 5 years of age with a URI of less than 7 days' duration. Methods: Children were randomly assigned to receive an ADC (brompheniramine maleate–phenylpropanolamine hydrochloride) or placebo as needed for URI symptoms. Two hours after each dose of study medication, changes in the child”s runny nose, nasal congestion, cough, and sleep status were assessed by means of a standardized questionnaire. Results: A total of 175 responses were recorded for 59 patients. There were no statistically significant differences in symptom improvement between the ADC and the placebo group (runny nose, p = 0.48; nasal congestion, p = 0.94; cough, p = 0.66). However, the proportion of children asleep 2 hours after receiving the ADC was significantly higher than the proportion receiving placebo (46.6% vs 26.5%; p = 0.01). Results were unchanged after control for the correlated nature of repeated responses, age, symptom duration, use of acetaminophen, time that the medication was given, and parental desire for medication. Conclusions: The ADC was equivalent to placebo in providing temporary relief of URI symptoms in preschool children. However, the ADC did have significantly greater sedative effects than did placebo. (J Pediatr 1997;130:463-6)" @default.
- W2018077130 created "2016-06-24" @default.
- W2018077130 creator A5006777013 @default.
- W2018077130 creator A5017491136 @default.
- W2018077130 creator A5018478903 @default.
- W2018077130 creator A5052354041 @default.
- W2018077130 creator A5067020149 @default.
- W2018077130 creator A5070085328 @default.
- W2018077130 date "1997-03-01" @default.
- W2018077130 modified "2023-10-01" @default.
- W2018077130 title "Is an antihistamine-decongestant combination effective in temporarily relieving symptoms of the common cold in preschool children?" @default.
- W2018077130 cites W1503233685 @default.
- W2018077130 cites W1578181538 @default.
- W2018077130 cites W1978279533 @default.
- W2018077130 cites W1980192174 @default.
- W2018077130 cites W1998467513 @default.
- W2018077130 cites W2043257375 @default.
- W2018077130 cites W2047899642 @default.
- W2018077130 cites W2259686282 @default.
- W2018077130 cites W4205568346 @default.
- W2018077130 cites W4249451171 @default.
- W2018077130 doi "https://doi.org/10.1016/s0022-3476(97)70211-7" @default.
- W2018077130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9063425" @default.
- W2018077130 hasPublicationYear "1997" @default.
- W2018077130 type Work @default.
- W2018077130 sameAs 2018077130 @default.
- W2018077130 citedByCount "84" @default.
- W2018077130 countsByYear W20180771302012 @default.
- W2018077130 countsByYear W20180771302013 @default.
- W2018077130 countsByYear W20180771302014 @default.
- W2018077130 countsByYear W20180771302015 @default.
- W2018077130 countsByYear W20180771302016 @default.
- W2018077130 countsByYear W20180771302017 @default.
- W2018077130 countsByYear W20180771302018 @default.
- W2018077130 countsByYear W20180771302020 @default.
- W2018077130 countsByYear W20180771302021 @default.
- W2018077130 countsByYear W20180771302022 @default.
- W2018077130 countsByYear W20180771302023 @default.
- W2018077130 crossrefType "journal-article" @default.
- W2018077130 hasAuthorship W2018077130A5006777013 @default.
- W2018077130 hasAuthorship W2018077130A5017491136 @default.
- W2018077130 hasAuthorship W2018077130A5018478903 @default.
- W2018077130 hasAuthorship W2018077130A5052354041 @default.
- W2018077130 hasAuthorship W2018077130A5067020149 @default.
- W2018077130 hasAuthorship W2018077130A5070085328 @default.
- W2018077130 hasConcept C126322002 @default.
- W2018077130 hasConcept C141071460 @default.
- W2018077130 hasConcept C142724271 @default.
- W2018077130 hasConcept C203014093 @default.
- W2018077130 hasConcept C204787440 @default.
- W2018077130 hasConcept C27081682 @default.
- W2018077130 hasConcept C2776880894 @default.
- W2018077130 hasConcept C2777844070 @default.
- W2018077130 hasConcept C2778136109 @default.
- W2018077130 hasConcept C2778311950 @default.
- W2018077130 hasConcept C2778385066 @default.
- W2018077130 hasConcept C2780805593 @default.
- W2018077130 hasConcept C2910477827 @default.
- W2018077130 hasConcept C42219234 @default.
- W2018077130 hasConcept C71924100 @default.
- W2018077130 hasConceptScore W2018077130C126322002 @default.
- W2018077130 hasConceptScore W2018077130C141071460 @default.
- W2018077130 hasConceptScore W2018077130C142724271 @default.
- W2018077130 hasConceptScore W2018077130C203014093 @default.
- W2018077130 hasConceptScore W2018077130C204787440 @default.
- W2018077130 hasConceptScore W2018077130C27081682 @default.
- W2018077130 hasConceptScore W2018077130C2776880894 @default.
- W2018077130 hasConceptScore W2018077130C2777844070 @default.
- W2018077130 hasConceptScore W2018077130C2778136109 @default.
- W2018077130 hasConceptScore W2018077130C2778311950 @default.
- W2018077130 hasConceptScore W2018077130C2778385066 @default.
- W2018077130 hasConceptScore W2018077130C2780805593 @default.
- W2018077130 hasConceptScore W2018077130C2910477827 @default.
- W2018077130 hasConceptScore W2018077130C42219234 @default.
- W2018077130 hasConceptScore W2018077130C71924100 @default.
- W2018077130 hasIssue "3" @default.
- W2018077130 hasLocation W20180771301 @default.
- W2018077130 hasLocation W20180771302 @default.
- W2018077130 hasOpenAccess W2018077130 @default.
- W2018077130 hasPrimaryLocation W20180771301 @default.
- W2018077130 hasRelatedWork W1590322802 @default.
- W2018077130 hasRelatedWork W1908067884 @default.
- W2018077130 hasRelatedWork W2018077130 @default.
- W2018077130 hasRelatedWork W2047899642 @default.
- W2018077130 hasRelatedWork W2114975889 @default.
- W2018077130 hasRelatedWork W2413080254 @default.
- W2018077130 hasRelatedWork W2587081950 @default.
- W2018077130 hasRelatedWork W2978702344 @default.
- W2018077130 hasRelatedWork W3161592305 @default.
- W2018077130 hasRelatedWork W4241965724 @default.
- W2018077130 hasVolume "130" @default.
- W2018077130 isParatext "false" @default.
- W2018077130 isRetracted "false" @default.
- W2018077130 magId "2018077130" @default.
- W2018077130 workType "article" @default.